| Type | Description |
|---|---|
| Definition | mucin 5, subtype B, tracheobronchial |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 13:00:00 | Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin. | 32348677 |
| 2020-05-09 11:26:00 | Muc5b-overexpressing mice demonstrated significantly larger cysts when exposed to repeated bleomycin. Mice injured with H1N1 demonstrated significant increases in Muc5b protein over baseline 4 weeks later. Muc5b may play a role in honeycomb formation in lung fibrosis, or may sensitize cells to genotoxic stress, worsening injury, but Muc5b does not appear to be necessary for HC changes in response to H1N1 or bleomycin. | 31573335 |
| 2019-09-07 12:27:00 | It found that terminally O-glycosylated chains of Muc5b were sialylated but not fucosylated, whereas Muc5ac was fucosylated but not sialylated. | 31030254 |
| 2019-07-06 12:47:00 | MUC5B promoter variant is associated with higher C3 expression and suggest that the complement system may contribute to the pathogenesis of idiopathic pulmonary fibrosis. | 29565179 |
| 2019-04-20 10:30:00 | that Spdef regulates baseline Muc5b expression in respiratory epithelia but does not contribute to Muc5b regulation in a mouse model of Muc5b-predominant mucus obstruction caused by airway dehydration | 29579396 |
| Type | IDs |
|---|---|
| Synonymous | 2300002I04Rik, A130042M24, AV085033, MUC5, MUC9, mucin 5b |
| Gene |
UniProtKB-ID:
Q8BYW0_MOUSE,
Q9CV93_MOUSE,
E9Q5I3_MOUSE
UniprotKB:
Q8BYW0,
Q9CV93,
E9Q5I3
UniParc:
UPI00000E7FD2,
UPI00000EA4CB,
UPI00015294DE
EMBL:
AK037730,
AK009011,
AC175742,
AL772165
Ensembl:
ENSMUSG00000066108
KO:
mmu:74180
|
| Nucleutide sequences |
EMBL-CDS:
BAC29860.1,
BAB26024.1
Ensembl_TRS:
ENSMUST00000165147
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000128276
RefSeq:
XP_006508716.2,
NP_083077.2
|
| Others |
UniRef100:
UniRef100_Q9CV93,
UniRef100_E9Q5I3
UniRef90:
UniRef90_E9Q5I3,
UniRef90_Q9CV93
UniRef50:
UniRef50_E9Q5I3,
UniRef50_Q9CV93
UniGene:
Mm.200752
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员