| Type | Description |
|---|---|
| Definition | roundabout guidance receptor 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 13:02:00 | Robo4-mediated pancreatic endothelial integrity decreases inflammation and islet destruction in autoimmune diabetes. | 31916652 |
| 2020-05-16 10:06:00 | a novel functional role for Robo4 in endothelial cell function and metabolic homeostasis in white adipose tissue, with Robo4 deletion protecting against endothelial and metabolic dysfunction associated with a HFD. | 30825241 |
| 2018-09-29 10:13:00 | Robo4 inhibits angiogenesis and vessel permeability independently of its cytoplasmic domain. Robo4 deletion enhances permeability and revascularization in oxygen-induced retinopathy (OIR) and accelerates cutaneous wound healing. | 27882935 |
| 2016-10-29 10:53:00 | endothelial Robo4 signaling is important for suppressing breast cancer growth and metastasis, and it can be targeted (enhanced) by administrating a small molecular drug. | 26778715 |
| 2015-09-12 11:33:00 | Robo4 vaccines induce antibodies that retard tumor growth. | 25348086 |
| Type | IDs |
|---|---|
| Synonymous | 1200012D01Rik, AI593217 |
| Gene |
UniProtKB-ID:
ROBO4_MOUSE,
A0A0R4J197_MOUSE,
D3Z4M4_MOUSE,
A0A1L1SUF8_MOUSE
UniprotKB:
Q8C310,
A0A0R4J197,
D3Z4M4,
A0A1L1SUF8
UniParc:
UPI0000D77B27,
UPI00015B3BF4,
UPI0000003E92,
UPI001461888D,
UPI00003A9329,
UPI000022EF8B
EMBL:
AK004723,
AF536772,
AC138284,
AK087355,
BC020129
Ensembl:
ENSMUSG00000032125
KO:
mmu:74144
|
| Nucleutide sequences |
EMBL-CDS:
BAC39850.1,
AAQ10749.1,
AAH20129.1,
BAB23506.2
Ensembl_TRS:
ENSMUST00000214185,
ENSMUST00000102895,
ENSMUST00000102895,
ENSMUST00000239486,
ENSMUST00000115046,
ENSMUST00000214185
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000150722,
ENSMUSP00000099959,
ENSMUSP00000099959,
ENSMUSP00000159318,
ENSMUSP00000110698,
ENSMUSP00000150722
RefSeq:
XP_036011249.1,
XP_036011251.1,
NP_083059.3,
XP_011240917.1,
XP_036011250.1,
XP_006510710.1,
XP_006510708.1,
XP_006510707.1,
NP_001296319.2
|
| Others |
UniRef100:
UniRef100_D3Z4M4,
UniRef100_A0A0R4J197,
UniRef100_Q8C310
UniRef90:
UniRef90_Q8C310
UniRef50:
UniRef50_Q8WZ75
UniGene:
Mm.485070
CCDS:
CCDS80976.1,
CCDS22977.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员