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74137 Nuak2

74137

Nuak2

NUAK family, SNF1-like kinase, 2

protein-coding

Mus musculus

基因描述

Type Description
Definition NUAK family, SNF1-like kinase, 2

研究结论

Date Results Publications
2020-02-29 12:35:00 These results demonstrate that SNARK is highly expressed in the heart and HL1 cardiomyocytes, and that SNARK is phosphorylated in response to ischemia and exercise and functions in the regulation of cardiac glucose transport. 30256437
2020-01-18 10:58:00 A role for SNARK in the maintenance of skeletal muscle mass under cachexia conditions. 31387190
2018-12-22 10:45:00 Using liver cancer as a model, NUAK2 was identified as an essential mediator of YAP-driven hepatomegaly and tumorigenesis in vivo. 30446657
2018-05-26 10:48:00 Data (including data from studies in knockout and transgenic mice) suggest that Nuak2/Snark is involved in both adipose inflammation and energy metabolism in white/brown adipocytes; Nuak2/Snark appears to regulate thermogenesis in brown adipocytes. 29298809
2016-07-16 10:09:00 These findings reveal a critical role for SNARK in myocyte survival and the maintenance of muscle mass with age. 26690705

名称对应

Type IDs
Synonymous 1200013B22Rik, Omphk2, Snark, mKIAA0537
Gene
UniProtKB-ID: NUAK2_MOUSE
UniprotKB: Q8BZN4
UniParc: UPI000005FB41, UPI0000021158
EMBL: BC046833, BC033302, AK033672, AK034082, AK004737
Ensembl: ENSMUSG00000009772
KO: mmu:74137
Nucleutide sequences
EMBL-CDS: BAC28575.1, BAC28421.1, AAH46833.1, AAH33302.1, BAB23518.1
Ensembl_TRS: ENSMUST00000072177, ENSMUST00000082125
Protein sequencees
Ensembl_PRO: ENSMUSP00000072039, ENSMUSP00000080769
RefSeq: XP_036009855.1, XP_006529972.1, NP_083054.1, NP_001181954.1, XP_036009854.1
Others
UniRef100: UniRef100_Q8BZN4
UniRef90: UniRef90_Q8BZN4
UniRef50: UniRef50_Q66HE5
UniGene: Mm.100666
CCDS: CCDS15283.1, CCDS56642.1

全选

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研究热度

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