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7411 VBP1

7411

VBP1

VHL binding protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition VHL binding protein 1

研究结论

Date Results Publications
2021-01-09 13:33:00 The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation. 33137104
2018-11-03 11:55:00 Data show that von Hippel-Lindau-binding protein 1 (VBP1) enhances the stability of von Hippel-Lindau tumor suppressor protein (pVHL) and facilitates pVHL-mediated ubiquitination of hypoxia-inducible factor 1, alpha subunit (HIF-1alpha). 29121446
2014-02-08 10:05:00 VBP1 acts together with p97 to regulate hMSH4 degradation. 23964080
2010-01-21 00:00:00 binds to HIF-1 alpha and regulates the function of HIF-1 alpha 12613020
2010-01-21 00:00:00 VBP1 and cullin2/von Hippel-Lindau are required for proper HIV-1 expression at a step between integrase-dependent proviral integration into the host genome and transcription of viral genes 17698809

名称对应

Type IDs
Synonymous HIBBJ46, PFD3, PFDN3, VBP-1
Gene
UniProtKB-ID: PFD3_HUMAN, D3DWY7_HUMAN, Q6FH24_HUMAN
UniprotKB: P61758, D3DWY7, Q6FH24
UniParc: UPI00017A8151, UPI0000000768, UPI0000D4B3CE, UPI0000163894
EMBL: CH471172, AK313420, BT019604, CR541932, AL356738, AK301646, U96759, BX682237, BC046094, U56833, Y17394
Ensembl: ENSG00000155959
KO: hsa:7411
Nucleutide sequences
EMBL-CDS: CAA76761.1, BAG63125.1, AAH46094.1, AAC50617.1, BAG36212.1, AAV38411.1, AAC23907.1, CAI41469.1, EAW72630.1, EAW72628.1, CAG46730.1, EAW72627.1
Gene_ORFName: hCG_17616, hCG_17616
Ensembl_TRS: ENST00000535916, ENST00000286428, ENST00000625964
Protein sequencees
Ensembl_PRO: ENSP00000438694, ENSP00000486053, ENSP00000286428
RefSeq: NP_003363.1, NP_001290473.1, NP_001290472.1, NP_001290474.1
Others
UniRef100: UniRef100_P61758, UniRef100_Q6FH24
UniRef90: UniRef90_G1LR48, UniRef90_P61758
UniRef50: UniRef50_P61758
UniGene: Hs.436803
CCDS: CCDS14765.1, CCDS78525.1

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