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74104 Abcb6

74104

Abcb6

ATP-binding cassette, sub-family B (MDR/TAP), member 6

protein-coding

Mus musculus

基因描述

Type Description
Definition ATP-binding cassette, sub-family B (MDR/TAP), member 6

研究结论

Date Results Publications
2018-09-08 11:32:00 homozygous disruption of the Abcb6 gene in mice exacerbates porphyria phenotypes in the mouse model. 27507172
2015-07-04 16:17:00 liver extracts from Abcb6-deficient mice suppress P450 expression in human primary hepatocytes, suggest that this mouse model may provide an opportunity to understand the physiological signals and the mechanisms involved in negative regulation of P450s 25623066
2014-05-24 10:54:00 Identify a new role of ABCB6 in preventing atherosclerosis development by dampening platelet production, reactivity, and chemokine (C-C motif) ligand 5 deposition in atherosclerotic lesions. 24504733
2012-12-08 10:02:00 Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR) 22761424
2012-06-23 10:47:00 Abcb6 is the sole ATP-dependent porphyrin importer, and loss of Abcb6 produces up-regulation of heme and iron pathways necessary for normal development. 22294697

名称对应

Type IDs
Synonymous 1200005B17Rik
Gene
UniProtKB-ID: ABCB6_MOUSE
UniprotKB: Q9DC29
UniParc: UPI0000022824
EMBL: AK168642, BC006634, AK004605, AK150853, AK151165, AK152584
Ensembl: ENSMUSG00000026198
KO: mmu:74104
Nucleutide sequences
EMBL-CDS: AAH06634.1, BAE29909.1, BAE40501.1, BAE30168.1, BAB23404.1, BAE31334.1
Ensembl_TRS: ENSMUST00000027396
Protein sequencees
Ensembl_PRO: ENSMUSP00000027396
RefSeq: NP_076221.1, XP_006496615.1
Others
UniRef100: UniRef100_Q9DC29
UniRef90: UniRef90_Q9DC29
UniRef50: UniRef50_Q9NP58
UniGene: Mm.28663
CCDS: CCDS15065.1

全选

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研究热度

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