| Type | Description |
|---|---|
| Definition | phospholipase C, epsilon 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:59:00 | Results suggest that phospholipase C epsilon 1 (PLCepsilon1) is a potential regulator of tumor-infiltrating lymphocytes, functioning, at least in part, at the level of T cell trafficking and recruitment. | 31867717 |
| 2020-07-18 12:21:00 | Plce1 deficiency in mice predisposes to glomerular damage secondary to hypertensive insults. | 32223311 |
| 2017-11-25 15:14:00 | The first SNP rs29972765 is located in a gene desert on chromosome 18, about 72 kb upstream of Skor2 . The second SNP rs30415957 resides in the intron of Plce1.The remaining two SNPs (rs30768258 and rs31216810) are close to each other on chromosome 19, in the vicinity of Sorbs1. Knockdown of Sorbs1 by siRNA attenuates the induction of differentiation marker gene Prl8a2 | 27449513 |
| 2017-08-19 12:31:00 | 2-arachidonoylglycerol (2-AG) is an endogenous cannabinoid that depresses synaptic transmission through stimulation of CB1 receptors. Among the six isoforms of phospholipase C (PLC; PLCbeta, PLCgamma, PLCdelta, PLCepsilon, PLCzeta, PLCeta), only PLCbeta has been linked to 2-AG synthesis. Here we demonstrate that 8-CPT-2Me-cAMP, a selective agonist of the cAMP sensor protein Epac, enhances 2-AG-mediated synaptic depress... | 28209735 |
| 2017-06-24 12:46:00 | study shed light on a novel role of PLCepsilon in wound healing and provided new therapeutic approaches to target PLCepsilon for diminishing scar formation after injury | 28093232 |
| Type | IDs |
|---|---|
| Synonymous | 4933403A21Rik, PLCepsilon, Plce, mKIAA1516 |
| Gene |
UniProtKB-ID:
PLCE1_MOUSE
UniprotKB:
Q8K4S1
UniParc:
UPI00001ECF33
EMBL:
AK035546,
AC111023,
AB076247,
BC138349,
BC138350,
AK162236,
AK122521,
AF233885,
AC158905
Ensembl:
ENSMUSG00000024998
KO:
mmu:74055
|
| Nucleutide sequences |
EMBL-CDS:
BAC65803.1,
AAF40208.1,
AAI38350.1,
AAI38351.1,
BAE36807.1,
BAC29099.1,
BAC00906.1
Ensembl_TRS:
ENSMUST00000169713,
ENSMUST00000182481
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000130604,
ENSMUSP00000138360
RefSeq:
XP_006527458.1,
NP_062534.2,
XP_011245682.1,
XP_006527457.1
|
| Others |
UniRef100:
UniRef100_Q8K4S1
UniRef90:
UniRef90_Q8K4S1
UniRef50:
UniRef50_Q9P212-2
UniGene:
Mm.34031
CCDS:
CCDS37973.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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