| Type | Description |
|---|---|
| Definition | retinal degeneration 3 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-23 11:07:00 | Study describes a mouse model of Leber's Congenital Amaurosis type 1 and 12 with autosomal recessive mutation in rd3 gene. The substitution mutation in the Rd3 gene is predicted to cause a stop codon after residue 106. | 27150101 |
| 2017-05-20 14:16:00 | the main RetGC-binding interface on RD3 required for the negative regulation of the cyclase localizes to the Lys(87)-Leu(122) region. | 27471269 |
| 2015-05-09 12:35:00 | Direct association between RD3 and GCAP1 is important for GC1 targeting. | 25477517 |
| 2014-03-22 10:37:00 | Studies indicate that RD3 plays an essential role in the exit of guanylate cyclase from the endoplasmic reticulum and its trafficking to photoreceptor outer segments. | 23740938 |
| 2013-09-28 11:24:00 | Changes in gene expression associated with photoreceptor degeneration in the rd3 mouse model of Leber congenital amaurosis (LCA) type 12, are characterized. | 23687432 |
| Type | IDs |
|---|---|
| Synonymous | 3322402L07Rik, rd-3, rd3 |
| Gene |
UniProtKB-ID:
RD3_MOUSE,
Q05D96_MOUSE
UniprotKB:
Q8BRE0,
Q05D96
UniParc:
UPI00000EAE26,
UPI0000E57360
EMBL:
BC017602,
AK045045,
AB030195,
AK014383,
BC103778,
BC116935,
BC116937,
AC182412
Ensembl:
ENSMUSG00000049353,
ENSMUSG00000111723
KO:
mmu:74023
|
| Nucleutide sequences |
EMBL-CDS:
BAA92758.1,
AAI16938.1,
BAB29312.2,
BAC32196.1,
AAI16936.1,
AAI03779.1,
AAH17602.1
Ensembl_TRS:
ENSMUST00000217431,
ENSMUST00000180463,
ENSMUST00000181512,
ENSMUST00000175680
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000138049,
ENSMUSP00000150477,
ENSMUSP00000137756,
ENSMUSP00000135650
RefSeq:
XP_006497268.1,
NP_001290061.1,
NP_076216.3,
NP_001171371.2,
XP_006497269.1,
XP_036009770.1,
XP_036009772.1
|
| Others |
UniRef100:
UniRef100_Q05D96,
UniRef100_Q8BRE0
UniRef90:
UniRef90_Q05D96,
UniRef90_Q8BRE0
UniRef50:
UniRef50_Q05D96,
UniRef50_Q8BRE0
UniGene:
Mm.274393
CCDS:
CCDS15626.3
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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