| Type | Description |
|---|---|
| Definition | alsin Rho guanine nucleotide exchange factor |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 11:24:00 | two ALS-linked factors, SQSTM1 and ALS2, have distinct but additive protective roles against mutant SOD1-mediated toxicity by modulating neuronal proteostasis possibly through the autophagy-endolysosomal system. | 27439389 |
| 2016-12-17 11:22:00 | By taking advantage of this CSMN reporter line of AlsinKO, authors reveal that apical dendrite degeneration is a common cellular pathology for CSMN that become diseased for different causes. | 26755825 |
| 2013-03-02 13:17:00 | alsin and spartin may interact each other physically. | 22982304 |
| 2012-01-07 12:45:00 | Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity. | 21937428 |
| 2011-12-10 10:51:00 | these results suggest that Als2 is a binding partner of Uxt and Als2/Uxt interaction could be important for the activation of Nf-kappaB pathway. | 21907703 |
| Type | IDs |
|---|---|
| Synonymous | 3222402C23Rik, 9430073A21Rik, Als2cr6, Alsin, mKIAA1563 |
| Gene |
UniProtKB-ID:
ALS2_MOUSE
UniprotKB:
Q920R0
UniParc:
UPI0000F22050,
UPI00027DB78E
EMBL:
AC153652,
BC031479,
BC046828,
AK014320,
CH466548,
AB053307
Ensembl:
ENSMUSG00000026024
KO:
mmu:74018
|
| Nucleutide sequences |
EMBL-CDS:
EDL00124.1,
BAB29271.2,
BAB69016.1,
AAH46828.1,
AAH31479.1
Ensembl_TRS:
ENSMUST00000027178,
ENSMUST00000163058
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125753,
ENSMUSP00000027178
RefSeq:
NP_666221.1,
NP_001153420.2,
NP_082993.4
|
| Others |
UniRef100:
UniRef100_Q920R0
UniRef90:
UniRef90_Q920R0
UniRef50:
UniRef50_Q96Q42
UniGene:
Mm.272078,
Mm.474049
CCDS:
CCDS35583.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员