| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:20:00 | Comprehensive analysis of ubiquitin-specific protease 1 reveals its importance in hepatocellular carcinoma. | 32951278 |
| 2020-06-06 12:34:00 | Ubiquitin specific peptidase 1 (USP1) deubiquitinates and stabilizes histone demethylase lysine-specific demethylase 4A (KDM4A), which promotes recruitment of androgen receptor to the c-Myc gene enhancer. Inhibition of USP1 decreases prostate cancer cell proliferation and promotes response to therapeutic agent enzalutamide in a KDM4A-dependent manner. | 32133742 |
| 2020-05-16 12:41:00 | USP1 (ubiquitin specific peptidase 1) has been identified as a key player in the modulation of ULK1 K63-linked deubiquitination. | 30335599 |
| 2020-05-09 12:12:00 | USP1 is phosphorylated by ATM and ATR and binds to Snail. Knockout or pharmacological inhibition of USP1 increased platinum sensitivity and decreased metastatic dissemination in a Snail-dependent manner. | 31086816 |
| 2019-10-26 10:28:00 | High USP1 expression is associated with Glioma Tumorigenesis. | 30425057 |
| Type | IDs |
|---|---|
| Synonymous | UBP |
| Gene |
UniProtKB-ID:
UBP1_HUMAN
UniprotKB:
O94782
UniParc:
UPI00001379D4
EMBL:
BC050525,
BC018745,
AF117386,
CH471059,
AL117575,
BC032364,
AB208893,
AB014458,
AL117503
Ensembl:
ENSG00000162607
KO:
hsa:7398
|
| Nucleutide sequences |
EMBL-CDS:
CAB55999.1,
AAH18745.1,
EAX06585.1,
AAH32364.1,
EAX06586.1,
BAD92130.1,
BAA34703.1,
AAH50525.1,
AAD11441.1,
CAB55967.1
Ensembl_TRS:
ENST00000339950,
ENST00000371146
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000343526,
ENSP00000360188
RefSeq:
NP_003359.3,
NP_001017416.1,
NP_001017415.1
|
| Others |
UniRef100:
UniRef100_O94782
UniRef90:
UniRef90_O94782
UniRef50:
UniRef50_O94782
UniGene:
Hs.35086
CCDS:
CCDS621.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员