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73902 Psmb11

73902

Psmb11

proteasome (prosome, macropain) subunit, beta type, 11

protein-coding

Mus musculus

基因描述

Type Description
Definition proteasome (prosome, macropain) subunit, beta type, 11

研究结论

Date Results Publications
2019-10-26 11:28:00 We conclude that PSMB11 has pervasive effects on both CD4 and CD8 thymocytes via regulation of gene expression in cortical thymic epithelial cells. 30567730
2018-11-17 12:13:00 Study report the identification of a highly conserved Foxn1-binding sequence that is located proximal to the beta5t-coding sequence in the mouse genome. This cis-regulatory element is indeed essential for the optimal expression of beta5t in cortical thymic epithelial cells and the optimal production of CD8+ T cells. 28176764
2016-04-09 11:30:00 beta5t-containing thymoproteasomes contribute to the positive selection of CD8+ T cells by preferentially producing low-affinity TCR ligand peptides. 26099460
2014-09-27 12:45:00 The current data showed that impaired proteasomal function causes photoreceptor degeneration. 24994871
2013-08-31 12:01:00 Results indicate that the majority of thymic medullary epithelial cells (mTECs) are derived from beta5t-expressing progenitor cells. 23720310

名称对应

Type IDs
Synonymous 5830406J20Rik, beta5t
Gene
UniProtKB-ID: PSB11_MOUSE
UniprotKB: Q8BG41
UniParc: UPI00000EBA61
EMBL: BC117732, AB299436, AK041393, AK037368, AK162727, BC117733
Ensembl: ENSMUSG00000072423
KO: mmu:73902
Nucleutide sequences
EMBL-CDS: BAE37039.1, AAI17733.1, BAC30929.1, BAF63539.1, AAI17734.1, BAC29796.1
Ensembl_TRS: ENSMUST00000097177
Protein sequencees
Ensembl_PRO: ENSMUSP00000132140
RefSeq: NP_780413.1
Others
UniRef100: UniRef100_Q8BG41
UniRef90: UniRef90_Q8BG41
UniRef50: UniRef50_A5LHX3
UniGene: Mm.32009
CCDS: CCDS49491.1

全选

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研究热度

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