| Type | Description |
|---|---|
| Definition | ubiquinol-cytochrome c reductase core protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 11:16:00 | our study as presented here identify the mitochondrial protein QCR2 as a novel suppressor of p53 to negatively regulate its stability and activity, and this suppression can be potentially reversed by another mitochondrial protein PHB. | 30674441 |
| 2018-11-10 11:59:00 | These results provided novel insights into the potential role of UQCRC2 in the tumorigenesis and progression of colorectal cancer | 30115536 |
| 2018-09-15 11:53:00 | Down-regulation of UQCRC2 partly reversed the inhibition of invasion/migration ability and chemoresistance in CDH18 overexpressed glioma cell lines. | 30078018 |
| 2013-08-31 12:04:00 | These data indicate that a homozygous missense mutation in UQCRC2 causes moderately impaired CIII function and severely decreased amounts of CIII and supercomplex, which would be the primary molecular pathogenesis in the patients. | 23281071 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| Type | IDs |
|---|---|
| Synonymous | MC3DN5, QCR2, UQCR2 |
| Gene |
UniProtKB-ID:
QCR2_HUMAN
UniprotKB:
P22695
UniParc:
UPI0000137A45
EMBL:
AK094006,
BC000484,
BC003136,
CH471249,
J04973
Ensembl:
ENSG00000140740
KO:
hsa:7385
|
| Nucleutide sequences |
EMBL-CDS:
AAH03136.1,
BAG52796.1,
AAH00484.1,
EAW50592.1,
AAA35710.1
Ensembl_TRS:
ENST00000268379
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000268379
RefSeq:
NP_003357.2
|
| Others |
UniRef100:
UniRef100_P22695
UniRef90:
UniRef90_P22695
UniRef50:
UniRef50_P22695
UniGene:
Hs.528803
CCDS:
CCDS10601.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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