| Type | Description |
|---|---|
| Definition | uracil DNA glycosylase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:48:00 | Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Proteins. | 32998246 |
| 2020-11-21 13:15:00 | Macromolecular crowding induces compaction and DNA binding in the disordered N-terminal domain of hUNG2. | 31855846 |
| 2020-04-25 11:48:00 | A common SNP in the UNG gene decreases ovarian cancer risk in BRCA2 mutation carriers. | 30747491 |
| 2019-11-30 11:36:00 | We identified a distinct UNG1 isoform variant that is targeted to the cell nucleus where it supports antibody class switching and repairs genomic uracil. We propose that the nuclear UNG1 variant, which in contrast to UNG2 lacks a PCNA-binding motif, may be specialized to act on ssDNA through its ability to bind RPA | 30838409 |
| 2019-10-05 12:59:00 | Data indicate that patients with a combined profile of uracil DNA glycosylase (UDG)/breast cancer 1, early onset protein (BRCA1) had the poorest outcome. | 30527192 |
| Type | IDs |
|---|---|
| Synonymous | DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2 |
| Gene |
UniProtKB-ID:
UNG_HUMAN,
E5KTA5_HUMAN,
E5KTA6_HUMAN
UniprotKB:
P13051,
E5KTA5,
E5KTA6
UniParc:
UPI000002E954,
UPI000002E951
EMBL:
AK291341,
HQ206238,
HQ206232,
HQ206239,
X89398,
HQ206254,
HQ206255,
HQ206240,
HQ206252,
HQ206257,
HQ206233,
HQ206246,
HQ206263,
HQ206245,
HQ206237,
HQ206249,
CH471054,
HQ206264,
HQ206230,
HQ206261,
Y09008,
HQ206250,
HQ206229,
HQ206236,
BC050634,
HQ206248,
HQ206260,
BC015205,
HQ206235,
HQ206242,
HQ206244,
HQ206227,
HQ206253,
HQ206259,
AK313552,
AF526277,
HQ206251,
HQ206262,
HQ206231,
HQ206226,
HQ206265,
HQ206243,
HQ206234,
HQ206228,
HQ206256,
HQ206241,
HQ206247,
HQ206258,
X15653
Ensembl:
ENSG00000076248
KO:
hsa:7374
|
| Nucleutide sequences |
EMBL-CDS:
CAA61579.1,
CAA33679.1,
EAW97846.1,
BAF84030.1,
EAW97847.1,
BAG36328.1,
CAA70211.1,
AAH15205.1,
AAM77695.1,
CAA61578.1,
AAH50634.1,
ADP92210.1,
ADP92190.1,
ADP92166.1,
ADP92182.1,
ADP92138.1,
ADP92160.1,
ADP92140.1,
ADP92212.1,
ADP92152.1,
ADP92150.1,
ADP92180.1,
ADP92136.1,
ADP92184.1,
ADP92172.1,
ADP92148.1,
ADP92170.1,
ADP92194.1,
ADP92164.1,
ADP92208.1,
ADP92168.1,
ADP92158.1,
ADP92186.1,
ADP92196.1,
ADP92162.1,
ADP92188.1,
ADP92202.1,
ADP92142.1,
ADP92198.1,
ADP92154.1,
ADP92176.1,
ADP92178.1,
ADP92156.1,
ADP92200.1,
ADP92134.1,
EAW97849.1,
ADP92192.1,
ADP92146.1,
ADP92206.1,
ADP92174.1,
ADP92204.1,
ADP92144.1,
ADP92163.1,
ADP92173.1,
ADP92143.1,
ADP92189.1,
ADP92135.1,
ADP92203.1,
ADP92137.1,
ADP92157.1,
ADP92183.1,
ADP92213.1,
ADP92149.1,
ADP92177.1,
ADP92139.1,
EAW97848.1,
ADP92207.1,
ADP92185.1,
ADP92153.1,
ADP92141.1,
ADP92181.1,
ADP92197.1,
ADP92159.1,
ADP92193.1,
ADP92209.1,
ADP92205.1,
ADP92211.1,
ADP92179.1,
ADP92147.1,
ADP92175.1,
ADP92165.1,
ADP92169.1,
ADP92199.1,
ADP92145.1,
ADP92167.1,
EAW97850.1,
ADP92155.1,
ADP92151.1,
ADP92191.1,
ADP92171.1,
ADP92201.1,
ADP92187.1,
ADP92161.1,
ADP92195.1
Gene_ORFName:
hCG_38494,
hCG_38494
Ensembl_TRS:
ENST00000336865,
ENST00000242576
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000337398,
ENSP00000242576
RefSeq:
NP_550433.1,
NP_003353.1
|
| Others |
UniRef100:
UniRef100_P13051,
UniRef100_E5KTA6
UniRef90:
UniRef90_A0A0D9S2V7,
UniRef90_P13051
UniRef50:
UniRef50_P13051
UniGene:
Hs.191334
CCDS:
CCDS9124.1,
CCDS9125.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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Ensembl: {{protein.proteinEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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