| Type | Description |
|---|---|
| Definition | mucin 16 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 11:59:00 | Authors confirm that MUC16 inhibits cytolysis by human NK cells as well as the formation of NK-tumor conjugates. Mice implanted with MUC16-knockdown OVCAR-3 show >2-fold increase in survival compared to controls. Murine NK cells and macrophages are more efficient at lysing MUC16-knockdown cells. | 30626487 |
| 2017-09-09 11:53:00 | Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.( | 28287406 |
| 2016-05-21 12:05:00 | MAMs MUC1 and MUC16 contribute to the maintenance of immune homeostasis at the ocular surface by limiting TLR-mediated innate immune responses. | 25563498 |
| 2015-08-15 10:09:00 | MUC16 functions as an oncogene. The cytoplasmic tail is critical for MUC16 oncogenic properties. | 25338620 |
| 2010-05-10 12:12:00 | Data show that intraperitoneal injections of living CA 125 positive cells of OVCAR-3 cell line, and boosted by intravenous injection of the purified extracellular domain of CA 125 was found to have excellent immunoreactivity for CA 125 mAb production. | 20054105 |
| Type | IDs |
|---|---|
| Synonymous | 1110008I14Rik, Ca125, Gm1480, Gm21044 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
NP_001365177.1,
XP_011240938.1,
XP_011240936.1
|
| Others |
UniGene:
Mm.490076
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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