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7372 UMPS

7372

UMPS

uridine monophosphate synthetase

protein-coding

Homo sapiens

基因描述

Type Description
Definition uridine monophosphate synthetase

研究结论

Date Results Publications
2021-03-20 13:27:00 LncRNA SNORD3A specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression. 32382150
2017-08-26 10:29:00 Partial UMPS-deficiency should be included in the differential diagnosis of mild orotic aciduria. 28205048
2017-06-24 11:14:00 The UMPS 638 CC genotype might be a candidate biomarker predicting toxicity in patients receiving tegafur-uracil/leucovorin-based preoperative chemoradiation for locally advanced rectal cancer 28347333
2014-02-22 11:46:00 OPRT transition state analogues identify crucial components of potent inhibitors targeting OPRT enzymes. 24158442
2013-09-07 11:29:00 The observed mutations, aberrant splicing and downregulation of UMPS represent novel mechanisms for acquired 5-FU resistance in colorectal cancer 22249354

名称对应

Type IDs
Synonymous OPRT
Gene
UniProtKB-ID: UMPS_HUMAN, A8K5J1_HUMAN
UniprotKB: P11172, A8K5J1
UniParc: UPI00017FAC1C, UPI000153D319, UPI00005054E7, UPI0000001223
EMBL: J03626, AB041359, D86230, BC007511, AY691629, EU921886, CR456787, KU178375, AB062285, AL080099, D86227, EU921895, M36661, AK291306, BC000364, AC022336, EU921891, CH471052, D86228
Ensembl: ENSG00000114491
KO: hsa:7372
Nucleutide sequences
EMBL-CDS: AAA61256.1, BAB20663.1, BAA19920.1, BAB93468.1, CAB45710.3, BAA19921.1, AAT85801.1, AAA61255.1, ACH48229.1, AAH07511.1, BAA19923.1, CAG33068.1, AAH00364.1, ACH48233.1, ALQ33833.1, BAF83995.1, ACH48224.1, EAW79408.1
Gene_ORFName: OK/SW-cl.21, hCG_1780791
Ensembl_TRS: ENST00000232607
Protein sequencees
Ensembl_PRO: ENSP00000232607
RefSeq: NP_000364.1
Others
UniRef100: UniRef100_P11172
UniRef90: UniRef90_P11172
UniRef50: UniRef50_P11172
UniGene: Hs.2057
CCDS: CCDS3029.1

全选

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