| Type | Description |
|---|---|
| Definition | uridine-cytidine kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:03:00 | survival analysis showed that only high methylation of cg0927774 was associated with better OS and RFS of HCC patients. Based on the findings above, we infer that UCK2 upregulation might be a valuable prognostic marker in hepatocellular carcinoma. The methylation of status cg0927774 might play a critical role in its expression | 30304569 |
| 2019-10-05 11:52:00 | Lung cancer patients with high UCK2 expression had poorer first progression survival and overall survival than patients with low UCK2 expression. Cytology experiments show that knockdown of UCK2 could suppress the proliferation and migration of lung cancer cells. Study indicated that UCK2 might be a potential early diagnostic and prognostic biomarker for lung cancer. | 31278886 |
| 2019-07-06 12:06:00 | High UCK2 expression is associated with hepatocellular carcinoma aggressiveness. | 30556610 |
| 2019-02-02 10:30:00 | Knockdown of endogenous UCK2 as well as overexpression of UCK1 resulted in decreased metabolism of uridine and cytidine and protected neuroblastoma cells from 3-deazauridine-induced toxicity. Subcellular localization studies showed that UCK1-GFP and UCK2-GFP were localized in the cell nucleus and cytosol, respectively. | 27239701 |
| 2017-08-05 10:11:00 | accumulation of RX-3117 nucleotides correlated with UCK2 expression. | 27612203 |
| Type | IDs |
|---|---|
| Synonymous | TSA903, UK, UMPK |
| Gene |
UniProtKB-ID:
UCK2_HUMAN
UniprotKB:
Q9BZX2
UniParc:
UPI000003AFFE,
UPI000006DBB4
EMBL:
BC002906,
BT006860,
D78335,
AL451074,
CR456857,
AB062451,
AL358115,
AF236637
Ensembl:
ENSG00000143179
KO:
hsa:7371
|
| Nucleutide sequences |
EMBL-CDS:
CAG33138.1,
AAK14053.1,
BAA11349.1,
AAP35506.1,
AAH02906.2,
BAB56162.1
Ensembl_TRS:
ENST00000470820,
ENST00000469256,
ENST00000367879
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356853,
ENSP00000476692,
ENSP00000476327
RefSeq:
NP_001350497.1,
NP_036606.2
|
| Others |
UniRef100:
UniRef100_Q9BZX2
UniRef90:
UniRef90_Q9BZX2
UniRef50:
UniRef50_Q9BZX2
UniGene:
Hs.458360
CCDS:
CCDS1252.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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