Type | Description |
---|---|
Definition | biogenesis of lysosomal organelles complex-1, subunit 2 |
Date | Results | Publications |
---|---|---|
2017-11-04 10:37:00 | BLOS2 physically interacted with Notch1 in endo-lysosomal trafficking of Notch1. The findings suggest that BLOS2 is a novel negative player in regulating Notch signaling through lysosomal trafficking to control multiple stem and progenitor cell homeostasis in vertebrates. | 27719760 |
2017-09-16 12:06:00 | These findings reveal that balanced control of Notch signaling by BLOS2 is required for HSC homeostasis during fetal liver hematopoiesis. | 28456747 |
2015-12-19 11:07:00 | SLX2 might get involved in chromosomes segregation during meiosis by interaction with BLOS2. | 24870619 |
2010-06-28 11:07:00 | WASH is a bimodular protein and a component of the BLOC-1 complex in which the C terminus is involved in Arp2/3-mediated actin nucleation, whereas the N-terminal portion is required for its regulation and localization in the cells | 20308062 |
2010-01-21 00:00:00 | Mutations in the human genes encoding Snapin and the BLOS proteins could underlie novel forms of Hermansky-Pudlak syndrome as seen in mouse models | 15102850 |
Type | IDs |
---|---|
Synonymous | 2410089B13Rik, BLOS2, Bloc1s2a |
Gene |
UniProtKB-ID:
BL1S2_MOUSE
UniprotKB:
Q9CWG9
UniParc:
UPI0000022572
EMBL:
AL928960,
AK010745,
BC065806
Ensembl:
ENSMUSG00000057506
KO:
mmu:73689
|
Nucleutide sequences |
EMBL-CDS:
BAB27155.1,
AAH65806.1
Ensembl_TRS:
ENSMUST00000079033
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000078042
RefSeq:
XP_011245671.1,
NP_082883.1
|
Others |
UniRef100:
UniRef100_Q9CWG9
UniRef90:
UniRef90_Q9CWG9
UniRef50:
UniRef50_Q6QNY1
UniGene:
Mm.124685
CCDS:
CCDS50445.1
|
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Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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