| Type | Description |
|---|---|
| Definition | autophagy related 16-like 2 (S. cerevisiae) |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 10:42:00 | results show that ATG16L1 and ATG16L2 contribute very distinctly to autophagy and cellular ontogeny in myeloid, lymphoid, and epithelial lineages. Dysregulation of any of these lineages could contribute to complex diseases like Crohn disease and systemic lupus erythematosus. | 31451676 |
| 2013-07-06 10:02:00 | IKKalpha, which may control autophagic protein degradation through its interaction with ATG16L2, plays a critical role in maintaining pancreatic acinar cell homeostasis, whose dysregulation promotes pancreatitis through p62 aggregate accumulation | 23563314 |
| 2012-06-23 10:06:00 | Despite forming the Atg12-Atg5-Atg16L2 complex, Atg16L2 is not recruited to phagophores and is mostly present in the cytosol. | 22082872 |
| Type | IDs |
|---|---|
| Synonymous | 2410118P20Rik |
| Gene |
UniProtKB-ID:
A16L2_MOUSE
UniprotKB:
Q6KAU8
UniParc:
UPI000173A793,
UPI000048702E,
UPI0000428E2A
EMBL:
AB476647,
AC107638,
AB476648,
AK131109,
BC060054
Ensembl:
ENSMUSG00000047767
KO:
mmu:73683
|
| Nucleutide sequences |
EMBL-CDS:
BAL42359.1,
BAD21359.1,
BAL42360.1,
AAH60054.1
Ensembl_TRS:
ENSMUST00000120267,
ENSMUST00000143630,
ENSMUST00000122116,
ENSMUST00000139609
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000117029,
ENSMUSP00000117387,
ENSMUSP00000113320,
ENSMUSP00000112500
RefSeq:
XP_006508293.1,
XP_030098883.1,
XP_030098882.1,
XP_036009368.1,
XP_006508290.1,
XP_006508288.1,
XP_036009370.1,
XP_006508294.1,
XP_036009369.1,
XP_011240220.1,
XP_011240218.1,
NP_001104581.1,
XP_006508291.1,
XP_006508289.1
|
| Others |
UniRef100:
UniRef100_Q6KAU8
UniRef90:
UniRef90_Q6KAU8
UniRef50:
UniRef50_Q6KAU8
UniGene:
Mm.275744
CCDS:
CCDS52329.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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