| Type | Description |
|---|---|
| Definition | tetratricopeptide repeat domain 21B |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:29:00 | MetAP2 inhibition reduces food intake and body weight in a ciliopathy mouse model of obesity. | 31877115 |
| 2020-09-10 16:37:00 | The role of IFT-A, an intraflagellar transport A (IFT-A) component, in hyperphagia, obesity, and metabolic syndrome was studied. | 31914634 |
| 2020-02-22 10:37:00 | This validated Gpr63 as a modifier of multiple Ttc21b neural phenotypes and strongly supports Gpr63 as a causal gene (i.e., a quantitative trait gene, QTG) within the Moaq1 QTL. | 31730647 |
| 2017-12-09 13:06:00 | Thm1-mutant ciliary defect diminishes sensitivity to feeding signals, which alters appetite regulation and leads to hyperphagia, obesity and metabolic disease. | 27482817 |
| 2017-09-09 11:55:00 | genetically ablated Kif3a, Ift88, and Ttc21b in a series of specific spatiotemporal domains. The resulting phenotypes allow us to draw several conclusions. First, we conclude that the Ttc21b cortical phenotype is not due to the activity of Ttc21b within the brain itself | 28291836 |
| Type | IDs |
|---|---|
| Synonymous | 2410066K11Rik, Thm1, aln, mKIAA1992 |
| Gene |
UniProtKB-ID:
TT21B_MOUSE,
E9PVK4_MOUSE
UniprotKB:
Q0HA38,
E9PVK4
UniParc:
UPI0000476A68,
UPI000058B265
EMBL:
AK173320,
AL844526,
AK132240,
DQ011164,
AL928586
Ensembl:
ENSMUSG00000034848
KO:
mmu:73668
|
| Nucleutide sequences |
EMBL-CDS:
BAE21052.1,
AAY79164.1,
BAD32598.1
Ensembl_TRS:
ENSMUST00000102718,
ENSMUST00000125446
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099779,
ENSMUSP00000131758
RefSeq:
XP_030107982.1,
NP_001277598.1,
NP_001041069.1,
XP_006500326.1
|
| Others |
UniRef100:
UniRef100_Q0HA38,
UniRef100_E9PVK4
UniRef90:
UniRef90_Q0HA38
UniRef50:
UniRef50_Q7Z4L5
UniGene:
Mm.250868
CCDS:
CCDS16076.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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