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7361 UGT1A

7361

UGT1A

UDP glucuronosyltransferase family 1 member A complex locus

other

Homo sapiens

基因描述

Type Description
Definition UDP glucuronosyltransferase family 1 member A complex locus

研究结论

Date Results Publications
2018-07-28 11:40:00 Genotypes of UGT1A and ABCB1 were significantly associated with changes in moxifloxacin pharmacokinetic parameters. 29210323
2018-07-14 11:58:00 The study demonstrates that miR-298 and miR-491-3p downregulates UGT1A expression. 29172698
2018-05-26 10:45:00 UGT1A7*3 allele emerged as a protective marker for hepatocellular carcinoma (HCC) development among both high-risk HBV/HCV-positive patients and healthy subjects. 28294511
2018-03-31 10:47:00 a common UGT1A haplotype, prevalent in 9% (homozygous) of the White population, significantly impairs the expression of UGT1A enzymes capable of cellular detoxification, which profoundly affects the physiological responsiveness towards the putative tobacco and environmental carcinogen benzo[alpha]pyrene 28300668
2017-05-06 11:32:00 Alternate UGT1A variants may thus be part of the expanding compendium of metabolic pathways involved in cancer biology. 28049773

名称对应

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Type IDs
Synonymous GNT1, UGT, UGT1, UGT1A