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7360 UGP2

7360

UGP2

UDP-glucose pyrophosphorylase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition UDP-glucose pyrophosphorylase 2

研究结论

Date Results Publications
2020-12-19 13:40:00 Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Are Reversed by Adding Galactose to the Growth Medium. 32188137
2020-09-19 16:22:00 Identification of UGP2 as a progression marker that promotes cell growth and motility in human glioma. 30816613
2018-08-18 11:46:00 High UGP2 expression is associated with malignant pancreatic lesions. 29347944
2013-08-03 10:57:00 This study provides clear evidence that the octameric state is a prerequisite for activity in the uridine diphosphate-glucose pyrophosphorylase. 23254995
2012-04-14 10:29:00 The crystal structure was determined and shown to form octamers through end-to-end and side-by-side interactions. Mutagenesis studies showed that both dissociation of octamers and mutations of the latch loop can significantly affect the activity. 22132858

名称对应

Type IDs
Synonymous UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379
Gene
UniProtKB-ID: UGPA_HUMAN, A0A140VKE1_HUMAN
UniprotKB: Q16851, A0A140VKE1
UniParc: UPI0000137AB0, UPI000000DB95
EMBL: BC000173, BC047004, HM005681, BC002954, U27460
Ensembl: ENSG00000169764
KO: hsa:7360
Nucleutide sequences
EMBL-CDS: AAH00173.2, AAH47004.1, AAH02954.1, AAB05640.1, AEE61278.1
Ensembl_TRS: ENST00000394417, ENST00000337130, ENST00000467648
Protein sequencees
Ensembl_PRO: ENSP00000377939, ENSP00000420793, ENSP00000338703
RefSeq: XP_024308892.1, NP_001364454.1, XP_024308888.1, XP_016860346.1, NP_001364453.1, NP_006750.3, NP_001364455.1, NP_001364457.1, XP_016860345.1, NP_001364458.1, XP_024308891.1, NP_001001521.1, XP_024308890.1, NP_001364456.1
Others
UniRef100: UniRef100_Q16851, UniRef100_A0A140VKE1
UniRef90: UniRef90_Q16851
UniRef50: UniRef50_Q16851
UniGene: Hs.516217
CCDS: CCDS1875.1, CCDS42690.1

全选

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