| Type | Description |
|---|---|
| Definition | vestigial like family member 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:41:00 | Study demonstrated that skin-directed overexpression of murine female-biased factor VGLL3 causes a severe lupus-like rash and systemic autoimmune disease that involves B cell expansion, autoantibody production, immune complex deposition, and end-organ damage. Results strongly implicate VGLL3 as a pivotal orchestrator of sex-biased autoimmunity. | 30996136 |
| 2013-12-28 12:12:00 | Loss of VGLL3 expression was observed in tumors derived from mouse xenograft models. | 23415753 |
| 2013-06-08 10:41:00 | vestigial-like 3 (Vgll3) is an inhibitor of adipogenesis | 23152581 |
| 2010-01-21 00:00:00 | In embryonic and fetal development VITO-2 is mainly expressed in the myogenic lineage.Later developmental stages it is found in the nervous system.In adult mice it was detected in skeletal muscle, heart, kidney, liver, brain. | 19118645 |
| Type | IDs |
|---|---|
| Synonymous | 1700110N18Rik, 4832416J22, C80713, Vgl-3, Vito-2 |
| Gene |
UniProtKB-ID:
E9Q1Y1_MOUSE
UniprotKB:
E9Q1Y1
UniParc:
UPI00002159E8
EMBL:
CT010565
Ensembl:
ENSMUSG00000091243
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000168064
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000131500
RefSeq:
NP_001355690.1,
NP_001355689.1,
NP_082848.1
|
| Others |
UniRef100:
UniRef100_E9Q1Y1
UniRef90:
UniRef90_D3ZZ09
UniRef50:
UniRef50_P85442
UniGene:
Mm.25670,
Mm.482366
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31138678 |
VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle. J Cell Sci Nicolas Figeac , Abdalla D Mohamed , Congshan Sun , Martin Schönfelder , David Matallanas , Amaya Garcia-Munoz , Edoardo Missiaglia , Elaina Collie-Duguid , Vanessa De Mello , Ajaybabu V Pobbati , Johanna Pruller , Oihane Jaka , Stephen D R Harridge , Wanjin Hong , Janet Shipley , Neil Vargesson , Peter S Zammit , Henning Wackerhage |
2019-07-05 | - |
| 30996136 |
The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity. JCI Insight Allison C Billi , Mehrnaz Gharaee-Kermani , Joseph Fullmer , Lam C Tsoi , Brett D Hill , Dennis Gruszka , Jessica Ludwig , Xianying Xing , Shannon Estadt , Sonya J Wolf , Syed Monem Rizvi , Celine C Berthier , Jeffrey B Hodgin , Maria A Beamer , Mrinal K Sarkar , Yun Liang , Ranjitha Uppala , Shuai Shao , Chang Zeng , Paul W Harms , Monique E Verhaegen , John J Voorhees , Fei Wen , Nicole L Ward , Andrzej A Dlugosz , J Michelle Kahlenberg , Johann E Gudjonsson |
2019-04-18 | - |
| 23415753 |
VGLL3 expression is associated with a tumor suppressor phenotype in epithelial ovarian cancer. Mol Oncol Karen Gambaro , Michael C J Quinn , Paulina M Wojnarowicz , Suzanna L Arcand , Manon de Ladurantaye , Véronique Barrès , Jean-Sébastien Ripeau , Ann M Killary , Elaine C Davis , Josée Lavoie , Diane M Provencher , Anne-Marie Mes-Masson , Mario Chevrette , Patricia N Tonin |
2013-06-01 | - |
| 23152581 |
Vestigial-like 3 is an inhibitor of adipocyte differentiation. J Lipid Res Daniel S Halperin , Calvin Pan , Aldons J Lusis , Peter Tontonoz |
2013-02-01 | - |
| 22967998 |
Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Dev. Biol. Tali Shalom-Barak , Xiaowen Zhang , Tianjiao Chu , W Timothy Schaiff , Janardan K Reddy , Jianming Xu , Yoel Sadovsky , Yaacov Barak |
2012-12-01 |
Hrct1,
Kcnj13,
Slc45a4,
Pkdcc,
Egln3,
Hsd17b11,
Aldoc,
Tpbpb,
Rnd2,
Cav1,
Clu,
Cxcr4,
Dgat1,
Sparcl1,
Emp2,
Epas1,
Epha4,
Fn1,
Gcgr,
Gcm1,
Ghrh,
Tsc22d3,
Gjb2,
Gm2a,
Hbegf,
Hpgd,
Hsd11b2,
Igfbp2,
Itk,
Ldhb,
Lepr,
Lifr,
Pdzd3,
Bbc3,
Maoa,
Mertk,
Mitf,
Mmp15,
Muc1,
Nfkb2,
Nid2,
Pcx,
Abcb1b,
Prkce,
Prl3b1,
Plat,
Pparg,
Ppargc1a,
Lgals3bp,
Prlr,
Pstpip1,
Ptger3,
Pthlh,
Rb1,
Scd2,
St8sia2,
Slc22a3,
Smpd1,
C2cd2,
Stc1,
Plekhh2,
Tgfb3,
Rnf144b,
Tpbpa,
Scgb1a1,
Vnn1,
Ywhaz,
Zfp185,
Vash2,
Megf9,
Tmem125,
Ncmap,
Sel1l3,
Eva1a,
Pxylp1,
Als2cl,
Nt5e,
Mab21l3,
Slc13a4,
Tmem255a,
Dcaf12l1,
Tceanc,
Vasn,
Map3k12,
Adck5,
Acot1,
Sgk2,
Nostrin,
L1td1,
Sgpp2,
Dppa5a,
Dkkl1,
Atp2a3,
Prdx4,
Irf6,
Ccrl2,
Rassf5,
St3gal6,
Car5b
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 19118645 |
Gene Expr. Patterns Michal Mielcarek , Izabela Piotrowska , Andre Schneider , Stefan Günther , Thomas Braun |
2009-03-01 |
Dll1,
Myf5,
Vgll2,
Tead4,
Vgll3
|
| 18287559 |
GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol Andrew P McMahon , Bruce J Aronow , Duncan R Davidson , Jamie A Davies , Kevin W Gaido , Sean Grimmond , James L Lessard , Melissa H Little , S Steven Potter , Elizabeth L Wilder , Pumin Zhang , GUDMAP project |
2008-04-01 | - |
| 17689488 |
Biochem Biophys Res Commun Michinori Kitagawa |
2007-10-05 | - |
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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