| Type | Description |
|---|---|
| Definition | upstream binding transcription factor |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | Protein kinase Ciota promotes UBF1-ECT2 binding on ribosomal DNA to drive rRNA synthesis and transformed growth of non-small-cell lung cancer cells. | 32350115 |
| 2020-07-04 11:27:00 | These results demonstrate the role of pNO40 in ribosomal RNA biosynthesis regulation by compromising UBF function in ribosomal DNA transcription activation with subsequent ribosomal RNA synthesis inhibition. | 31217076 |
| 2019-03-16 11:06:00 | mutant SEC23B binds to UBF transcription factor, with increased UBF transcription factor binding at the ribosomal DNA promoter. Our data indicate SEC23B has potential non-canonical COPII-independent function, particularly within the ribosome biogenesis pathway, and that may contribute to the pathogenesis of cancer-predisposition. | 29893852 |
| 2019-01-12 10:33:00 | Data underscore the importance of including UBTF E210K in the differential diagnosis of neuroregression and suggest that mainly gain-of-function mechanisms contribute to the pathogenesis of the UBTF E210K neuroregression syndrome. | 29300972 |
| 2018-01-20 10:40:00 | TP53INP2 promotes ribosome biogenesis through facilitating rRNA synthesis at the nucleolus | 27172002 |
| Type | IDs |
|---|---|
| Synonymous | CONDBA, NOR-90, UBF, UBF-1, UBF1, UBF2 |
| Gene |
UniProtKB-ID:
UBF1_HUMAN
UniprotKB:
P17480
UniParc:
UPI000013797C,
UPI000000D9D3
EMBL:
BC042297,
AK292518,
X53390,
X53461,
AK291733,
X56687
Ensembl:
ENSG00000108312
KO:
hsa:7343
|
| Nucleutide sequences |
EMBL-CDS:
CAA37548.1,
AAH42297.1,
CAA40016.1,
BAF84422.1,
BAF85207.1,
CAA37469.1
Ensembl_TRS:
ENST00000393606,
ENST00000533177,
ENST00000526094,
ENST00000343638,
ENST00000529383,
ENST00000302904,
ENST00000436088
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000390669,
ENSP00000435708,
ENSP00000302640,
ENSP00000345297,
ENSP00000377231,
ENSP00000432925,
ENSP00000437180
RefSeq:
XP_006722123.1,
XP_016880484.1,
NP_001070151.1,
XP_016880486.1,
XP_016880485.1,
XP_016880492.1,
XP_024306675.1,
XP_006722122.1,
XP_016880487.1,
XP_006722124.1,
XP_016880493.1,
NP_055048.1,
XP_016880490.1,
XP_016880489.1,
XP_016880488.1,
NP_001070152.1,
XP_016880491.1
|
| Others |
UniRef100:
UniRef100_P17480
UniRef90:
UniRef90_P17480
UniRef50:
UniRef50_P17480
UniGene:
Hs.89781
CCDS:
CCDS42346.1,
CCDS11480.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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