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7336 UBE2V2

7336

UBE2V2

ubiquitin conjugating enzyme E2 V2

protein-coding

Homo sapiens

基因描述

Type Description
Definition ubiquitin conjugating enzyme E2 V2

研究结论

Date Results Publications
2015-11-28 11:30:00 Data suggest that ubiquitin-conjugating enzyme E2 variant 2 (Ube2V2) and ring finger protein 4 (RNF4) together induce an active conformation of the ubiquitin-conjugating enzyme Ubc13-ubiquitin (Ubc13~Ub) thioester. 26148049
2015-08-22 11:35:00 Functional analysis of selected regulated proteins revealed that knockdown of HNRPD, PHB2 and UB2V2 can increase HCMV replication, while knockdown of A4 and KSRP resulted in decreased HCMV replication. 25910425
2014-06-14 13:03:00 suppression of hMMS2 reverses L-OHP tolerance in differentiated human colorectal carcinoma cells by promoting apoptosis 24846979
2012-10-13 10:38:00 the crystal structure of human OTUB1 in complex with human UBC13 and MMS2 22679021
2012-10-13 10:38:00 Data show RING finger (RNF) E3 ubiquitin ligase RNF8 dimerizes and binds to E2 ubiquitin-conjugating complex Ubc13/Mms2 with formation of Lys-63 ubiquitin chains, whereas the RNF168 RING domain is a monomer and does not catalyze Lys-6 ubiquitylation. 22589545

名称对应

Type IDs
Synonymous DDVIT1, DDVit-1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2
Gene
UniProtKB-ID: UB2V2_HUMAN, A0M8W4_HUMAN
UniprotKB: Q15819, A0M8W4
UniParc: UPI000006FD5B
EMBL: BC016332, BC007051, AK313447, CR407628, DQ003720, BT006744, BC062418, CH471068, BC028673, U62136, X98091, BC016710, AF049140
Ensembl: ENSG00000169139
KO: hsa:7336
Nucleutide sequences
EMBL-CDS: CAG28556.1, AAH16332.1, AAH28673.1, AAH62418.1, AAB04758.2, AAC05381.1, AAH07051.1, AAP35390.1, CAA66717.1, AAH16710.1, EAW86688.1, BAG36236.1, AAY16979.1
Gene_ORFName: hCG_1640505
Ensembl_TRS: ENST00000523111
Protein sequencees
Ensembl_PRO: ENSP00000428209
RefSeq: XP_016869297.1, XP_011515885.1, NP_003341.1
Others
UniRef100: UniRef100_Q15819
UniRef90: UniRef90_Q15819
UniRef50: UniRef50_Q15819
UniGene: Hs.491695
CCDS: CCDS43738.1

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