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7332 UBE2L3

7332

UBE2L3

ubiquitin conjugating enzyme E2 L3

protein-coding

Homo sapiens

基因描述

Type Description
Definition ubiquitin conjugating enzyme E2 L3

研究结论

Date Results Publications
2021-04-17 13:37:00 Synergistic activation of NF-kappaB by TNFAIP3 (A20) reduction and UBE2L3 (UBCH7) augment that synergistically elevate lupus risk. 32334614
2020-12-19 13:40:00 Overexpression of ubiquitin-conjugating enzyme E2 L3 in hepatocellular carcinoma potentiates apoptosis evasion by inhibiting the GSK3beta/p65 pathway. 32268166
2020-06-20 10:07:00 The rs59391722 allele in the promoter of the UBE2L3 gene was significantly associated with hepatitis B in both adults and children, and it increased the promoter activity of UBE2L3. Serum UBE2L3 protein levels were positively correlated with HBV viral load and hepatitis B e antigen levels in children with chronic hepatitis B. 30614547
2019-10-05 12:43:00 Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation. 30446597
2019-09-21 11:38:00 UBCH7/UBE2L3 catalyzes the conjugation of heterotypic ubiquitin chains on p27(Kip1) that are proteolytically incompetent 30113882

名称对应

Type IDs
Synonymous E2-F1, L-UBC, UBCH7, UbcM4
Gene
UniProtKB-ID: UB2L3_HUMAN, A0A024R1A4_HUMAN
UniprotKB: P68036, A0A024R1A4
UniParc: UPI0001AE62DF, UPI00001EA470, UPI0000029497
EMBL: CR456606, S81003, CH471095, X92962, AK293179, AK311761, AK299985, BC053368, AJ000519, AP000557, AP000558, AF300336, AP000553
Ensembl: ENSG00000185651
KO: hsa:7332
Nucleutide sequences
EMBL-CDS: AAB36017.1, BAG34704.1, CAA04156.1, EAW59459.1, AAG17922.1, CAA63538.1, BAG61806.1, AAH53368.1, CAG30492.1, BAG56722.1, EAW59460.1
Gene_ORFName: hCG_32558
Ensembl_TRS: ENST00000342192, ENST00000545681, ENST00000458578
Protein sequencees
Ensembl_PRO: ENSP00000445931, ENSP00000344259, ENSP00000400906
RefSeq: XP_016884424.1, NP_001243284.1, NP_001243285.1, NP_003338.1
Others
UniRef100: UniRef100_P68036
UniRef90: UniRef90_P68036
UniRef50: UniRef50_P68036
UniGene: Hs.108104
CCDS: CCDS13790.1, CCDS58796.1, CCDS58795.1

全选

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