| Type | Description |
|---|---|
| Definition | ubiquitin conjugating enzyme E2 G2 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-05 10:48:00 | UBE2G2 was crucial for the degradation of various immunoreceptors. UBE2J2, on the other hand, counteracted US2-induced endoplasmic reticulum-associated protein degradation by downregulating TRC8 expression. | 28743740 |
| 2017-05-13 13:27:00 | Further study discovered that the gp78 CUE domain works as a proofreading machine during the growth of K48-linked polyubiquitin chains to ensure the linkage specificity. Together, our studies uncover a novel mechanism underlying the linkage specificity determination of longer polyubiquitin chains. | 27067047 |
| 2014-03-01 13:00:00 | These results reveal an unanticipated mode of Ube2g2 self-association that allows Ube2g2 to effectively engage two ubiquitins to specifically synthesize Lys48-linked ubiquitin chains. | 24366945 |
| 2011-04-16 12:32:00 | The presence of the AUP1-Ube2g2 complex at LDs provides a direct molecular link between LDs and the cellular ubiquitination machinery. | 21127063 |
| 2011-03-26 12:10:00 | Lys-48-linked polyubiquitin chains may be designed to bind certain proteins like Ube2g2 such that the terminal ubiquitin subunit carrying the reactive Lys-48 side chain can be positioned properly for chain elongation regardless of chain length. | 21098018 |
| Type | IDs |
|---|---|
| Synonymous | UBC7 |
| Gene |
UniProtKB-ID:
UB2G2_HUMAN
UniprotKB:
P60604
UniParc:
UPI0000027925,
UPI00001B5789
EMBL:
CH471079,
AL163300,
BC001738,
AF032456,
AK290629,
BC011569,
BT006914,
BC008351
Ensembl:
ENSG00000184787
KO:
hsa:7327
|
| Nucleutide sequences |
EMBL-CDS:
BAF83318.1,
EAX09398.1,
EAX09399.1,
AAC32312.1,
AAP35560.1,
AAH08351.1,
CAB90551.1,
AAH11569.1,
AAH01738.1,
EAX09397.1,
EAX09395.1
Ensembl_TRS:
ENST00000345496,
ENST00000330942
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000331384,
ENSP00000338348
RefSeq:
NP_003334.2,
NP_872630.1,
XP_024307900.1,
NP_001189418.1
|
| Others |
UniRef100:
UniRef100_P60604
UniRef90:
UniRef90_P60604
UniRef50:
UniRef50_P60604
UniGene:
Hs.529420,
Hs.701398
CCDS:
CCDS13714.1,
CCDS33586.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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