| Type | Description |
|---|---|
| Definition | ubiquitin conjugating enzyme E2 G1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 10:32:00 | UBE2R2 alone had negligible ubiquitylation activity at physiological concentrations and the ablation of UBE2R1/2 had no effect on the stability of SCF substrates in cells. A genome-wide CRISPR screen revealed that an additional E2 enzyme, UBE2G1, buffers against the loss of UBE2R1/2. | 31868589 |
| 2019-01-26 11:39:00 | the ubiquitin-conjugating enzymes UBE2G1 and UBE2D3 cooperatively promote the K48-linked polyubiquitination of CRL4(CRBN) neomorphic substrates | 30234487 |
| 2015-04-25 11:51:00 | ubiquitin binding by the acidic loops of Ube2g1 and Ube2r1 enzymes distinguishes their Lys-48-ubiquitylation activities | 25471371 |
| 2011-09-17 11:27:00 | study reports that UBCH8 and UBE2G1 and UBE2G2 cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 and Cdt1, respectively | 21628527 |
| 2010-01-21 00:00:00 | In endoplasmic reticulum, involved in the degradation of type 2 iodothyronine selenodeiodinase | 12933904 |
| Type | IDs |
|---|---|
| Synonymous | E217K, UBC7, UBE2G |
| Gene |
UniProtKB-ID:
UB2G1_HUMAN
UniprotKB:
P62253
UniParc:
UPI0000028843
EMBL:
BC026288,
BT007416,
BC002775,
CH471108,
AK313059,
D78514
Ensembl:
ENSG00000132388
KO:
hsa:7326
|
| Nucleutide sequences |
EMBL-CDS:
EAW90446.1,
AAP36084.1,
EAW90445.1,
BAG35889.1,
AAH26288.2,
BAA11410.1,
AAH02775.1
Ensembl_TRS:
ENST00000396981
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380178
RefSeq:
NP_003333.1
|
| Others |
UniRef100:
UniRef100_P62253
UniRef90:
UniRef90_P62253
UniRef50:
UniRef50_P62253
UniGene:
Hs.741319
CCDS:
CCDS32532.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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