| Type | Description |
|---|---|
| Definition | ubiquitin conjugating enzyme E2 D3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:38:00 | Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3. | 32145025 |
| 2021-02-27 13:49:00 | UbcH5 Interacts with Substrates to Participate in Lysine Selection with the E3 Ubiquitin Ligase CHIP. | 32401531 |
| 2018-12-22 12:17:00 | Together with Riplet, Ube2D3 promotes covalent conjugation of polyubiquitin chains to RIG-I, while Ube2N preferentially facilitates production of unanchored chains. In the presence of these chains, RIG-I induces MAVS aggregation directly on the mitochondria. Data thus reveal two essential mechanisms underlying the activation of RIG-I and MAVS for triggering innate immune signaling in response to viral infection in cells. | 28469175 |
| 2018-01-27 11:48:00 | Findings indicate that UBE2D3 enhances radiosensitivity of EC109 cells by degradating hTERT through the ubiquitin proteolysis pathway. | 27105523 |
| 2016-03-19 10:16:00 | Data show that ubiquitin E2 enzymes UBE2D1/2/3 and E3 ligase RNF138 accumulate at DNA-damage sites and act at early resection stages by promoting CtIP protein ubiquitylation and accrual. | 26502057 |
| Type | IDs |
|---|---|
| Synonymous | E2(17)KB3, UBC4/5, UBCH5C |
| Gene |
UniProtKB-ID:
UB2D3_HUMAN,
A0A024RDH2_HUMAN,
D6RAH7_HUMAN
UniprotKB:
P61077,
A0A024RDH2,
D6RAH7
UniParc:
UPI000052C9EB,
UPI000006F42F,
UPI000000004D,
UPI00001B31EA
EMBL:
AK095822,
BC003395,
AF213884,
U39318,
BC066917,
BC037894,
AC018797,
CH471057,
CR456916,
DB045280
Ensembl:
ENSG00000109332
KO:
hsa:7323
|
| Nucleutide sequences |
EMBL-CDS:
EAX06143.1,
AAH03395.1,
CAG33197.1,
EAX06138.1,
AAF35234.1,
AAA91461.1,
AAH37894.1,
AAH66917.1,
BAC04632.1,
EAX06139.1,
EAX06145.1,
EAX06141.1,
EAX06142.1,
EAX06144.1
Gene_ORFName:
hCG_2028213
Ensembl_TRS:
ENST00000343106,
ENST00000394804,
ENST00000349311,
ENST00000321805,
ENST00000453744,
ENST00000394803,
ENST00000338145,
ENST00000357194,
ENST00000394801,
ENST00000507845,
ENST00000505207,
ENST00000502404,
ENST00000504211
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349722,
ENSP00000378280,
ENSP00000345285,
ENSP00000378283,
ENSP00000337208,
ENSP00000344069,
ENSP00000396901,
ENSP00000318494,
ENSP00000378282,
ENSP00000421904,
ENSP00000424359,
ENSP00000426620,
ENSP00000426586
RefSeq:
XP_016864073.1,
NP_871622.1,
XP_024309970.1,
NP_871615.1,
NP_871621.1,
NP_871616.1,
NP_871618.1,
NP_003331.1,
NP_871617.1,
NP_001287724.1,
NP_871620.1,
NP_871619.1
|
| Others |
UniRef100:
UniRef100_P61077
UniRef90:
UniRef90_P61077
UniRef50:
UniRef50_P61077
UniGene:
Hs.518773,
Hs.595430,
Hs.621366
CCDS:
CCDS3660.1,
CCDS3659.1,
CCDS3661.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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