| Type | Description |
|---|---|
| Definition | ubiquitin conjugating enzyme E2 D1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:04:00 | S-Nitrosylation at the active site decreases the ubiquitin-conjugating activity of ubiquitin-conjugating enzyme E2 D1 (UBE2D1), an ERAD-associated protein. | 32051088 |
| 2019-03-30 12:10:00 | Results showed that although UBE2D1 RNA was significantly upregulated in both lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) tissues; its expression was even higher in LUAD tissues than in LUSC. UBE2D1 RNA upregulation was associated with poor survival in LUAD patients, but not in LUSC suggesting it as an independent indicator of unfavorable prognosis in LUAD, but not in LUSC. | 30420903 |
| 2019-02-02 10:46:00 | Upregulation of UBE2D1 promoted HCC growth in vitro and in vivo by decreasing the p53 in ubiquitination-dependent pathway. High expression of UBE2D1 was attributed to the recurrent genomic copy number gain, which was associated with high serum IL-6 level of HCC patients. | 30482241 |
| 2019-01-12 12:11:00 | March-I undergoes lysine-independent ubiquitination by an as yet unidentified E3 ubiquitin ligase that, together with Ube2D1, regulates March-I expression | 29414787 |
| 2016-12-17 12:02:00 | The anaphase-promoting complex/cyclosome C activity in human cells is tuned by the combinatorial use of three E2 ubiquitin-conjugating enzymes, namely UBE2C, UBE2S, and UBE2D. | 26904940 |
| Type | IDs |
|---|---|
| Synonymous | E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A |
| Gene |
UniProtKB-ID:
UB2D1_HUMAN,
A0A024QZJ2_HUMAN,
A0A087WW00_HUMAN
UniprotKB:
P51668,
A0A024QZJ2,
A0A087WW00
UniParc:
UPI00004DC55A,
UPI0000001661
EMBL:
AJ293565,
X78140,
AC023170,
AC016396,
AF020761,
AJ272367,
BT007041,
BC005980,
BC015997,
AK291901,
CH471083,
AF257220
Ensembl:
ENSG00000072401
KO:
hsa:7321
|
| Nucleutide sequences |
EMBL-CDS:
AAH15997.1,
EAW54169.1,
CAA55019.1,
AAM81086.1,
CAC82177.1,
AAP35690.1,
BAF84590.1,
CAC82097.1,
AAH05980.1,
EAW54170.1
Gene_ORFName:
hCG_40954
Ensembl_TRS:
ENST00000373910,
ENST00000615793
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363019,
ENSP00000479814
RefSeq:
NP_001191809.1,
NP_003329.1
|
| Others |
UniRef100:
UniRef100_P51668,
UniRef100_A0A087WW00
UniRef90:
UniRef90_A0A2K6FAB6,
UniRef90_P51668
UniRef50:
UniRef50_A0A2K6FAB6,
UniRef50_P51668
UniGene:
Hs.129683
CCDS:
CCDS7252.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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