| Type | Description |
|---|---|
| Definition | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 12:58:00 | Short-term Resistance Training Increases APPL1 Content in the Liver and the Insulin Sensitivity of Mice Fed a Long-term High-fat Diet. | 30991419 |
| 2020-08-29 12:43:00 | Retrograde transport of Akt by a neuronal Rab5-APPL1 endosome. | 30792402 |
| 2020-08-15 19:06:00 | Acute physical exercise increases APPL1/PI3K signaling in the hypothalamus of lean mice. | 31206806 |
| 2020-02-29 10:46:00 | data demonstrated the essential role of APPL1 in regulating brown adipocytes thermogenesis via interaction with HDAC3, which may have potential therapeutic implications for treatment of obesity | 31390528 |
| 2019-10-26 12:20:00 | The results indicate physical exercise is capable of increasing APPL1 protein content in the hypothalamus of leptin stimulated-obese mice and modulating food intake. | 29705396 |
| Type | IDs |
|---|---|
| Synonymous | 2900057D21Rik, 7330406P05Rik, AI585782, AW209077, BB022931, C88264, DIP13 |
| Gene |
UniProtKB-ID:
DP13A_MOUSE
UniprotKB:
Q8K3H0
UniParc:
UPI00000289D6
EMBL:
AK146356,
AK173169,
AK045438,
AY113705,
AK033566,
AK013715,
BC063751,
AK049307,
BC019708
Ensembl:
ENSMUSG00000040760
KO:
mmu:72993
|
| Nucleutide sequences |
EMBL-CDS:
BAC33672.2,
BAB28966.3,
AAM55531.1,
BAC28364.1,
AAH63751.1,
BAD32447.1,
BAE27108.1,
BAC32367.1,
AAH19708.1
Ensembl_TRS:
ENSMUST00000036570
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000042875
RefSeq:
XP_017171703.1,
XP_030103910.1,
NP_660256.1,
XP_006519671.1
|
| Others |
UniRef100:
UniRef100_Q8K3H0
UniRef90:
UniRef90_Q9UKG1
UniRef50:
UniRef50_Q9UKG1
UniGene:
Mm.202322
CCDS:
CCDS26883.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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