| Type | Description |
|---|---|
| Definition | cytosolic arginine sensor for mTORC1 subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-08-27 12:08:00 | Study establishes the CASTOR1 homodimer and CASTOR1-CASTOR2 heterodimer as arginine sensors for the mTORC1 pathway. | 26972053 |
| Type | IDs |
|---|---|
| Synonymous | GATSL1, GATSL2 |
| Gene |
UniProtKB-ID:
CAST2_HUMAN
UniprotKB:
A6NHX0
UniParc:
UPI000013F134
EMBL:
BC147030,
AC245150,
BC147031,
BC150658
Ensembl:
ENSG00000274070
KO:
hsa:729438
|
| Nucleutide sequences |
EMBL-CDS:
AAI47031.1,
AAI47032.1,
AAI50659.1
Ensembl_TRS:
ENST00000616305
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000484732
RefSeq:
XP_016868063.1,
NP_001138536.1
|
| Others |
UniRef100:
UniRef100_A6NHX0
UniRef90:
UniRef90_A6NHX0
UniRef50:
UniRef50_A6NHX0
UniGene:
Hs.647048,
Hs.647505
CCDS:
CCDS75620.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26972053 |
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway. Cell Lynne Chantranupong , Sonia M Scaria , Robert A Saxton , Melanie P Gygi , Kuang Shen , Gregory A Wyant , Tim Wang , J Wade Harper , Steven P Gygi , David M Sabatini |
2016-03-24 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 12853948 |
The DNA sequence of human chromosome 7. Nature Ladeana W Hillier , Robert S Fulton , Lucinda A Fulton , Tina A Graves , Kymberlie H Pepin , Caryn Wagner-McPherson , Dan Layman , Jason Maas , Sara Jaeger , Rebecca Walker , Kristine Wylie , Mandeep Sekhon , Michael C Becker , Michelle D O'Laughlin , Mark E Schaller , Ginger A Fewell , Kimberly D Delehaunty , Tracie L Miner , William E Nash , Matt Cordes , Hui Du , Hui Sun , Jennifer Edwards , Holland Bradshaw-Cordum , Johar Ali , Stephanie Andrews , Amber Isak , Andrew Vanbrunt , Christine Nguyen , Feiyu Du , Betty Lamar , Laura Courtney , Joelle Kalicki , Philip Ozersky , Lauren Bielicki , Kelsi Scott , Andrea Holmes , Richard Harkins , Anthony Harris , Cynthia Madsen Strong , Shunfang Hou , Chad Tomlinson , Sara Dauphin-Kohlberg , Amy Kozlowicz-Reilly , Shawn Leonard , Theresa Rohlfing , Susan M Rock , Aye-Mon Tin-Wollam , Amanda Abbott , Patrick Minx , Rachel Maupin , Catrina Strowmatt , Phil Latreille , Nancy Miller , Doug Johnson , Jennifer Murray , Jeffrey P Woessner , Michael C Wendl , Shiaw-Pyng Yang , Brian R Schultz , John W Wallis , John Spieth , Tamberlyn A Bieri , Joanne O Nelson , Nicolas Berkowicz , Patricia E Wohldmann , Lisa L Cook , Matthew T Hickenbotham , James Eldred , Donald Williams , Joseph A Bedell , Elaine R Mardis , Sandra W Clifton , Stephanie L Chissoe , Marco A Marra , Christopher Raymond , Eric Haugen , Will Gillett , Yang Zhou , Rose James , Karen Phelps , Shawn Iadanoto , Kerry Bubb , Elizabeth Simms , Ruth Levy , James Clendenning , Rajinder Kaul , W James Kent , Terrence S Furey , Robert A Baertsch , Michael R Brent , Evan Keibler , Paul Flicek , Peer Bork , Mikita Suyama , Jeffrey A Bailey , Matthew E Portnoy , David Torrents , Asif T Chinwalla , Warren R Gish , Sean R Eddy , John D McPherson , Maynard V Olson , Evan E Eichler , Eric D Green , Robert H Waterston , Richard K Wilson |
2003-07-10 |
LOC100124402,
GAEC1,
CTAGE4,
LOC100128885,
LOC100129603,
EFCAB10,
C7orf72,
ZNF316,
LOC100132217,
CTAGE8,
RNU7-20P,
RNU7-83P,
GNL2P1,
RASA4B,
POM121B,
MTND1P3,
MOXD2P,
SPDYE2B,
ANKRD61,
SNRPCP19,
MTRNR2L6,
DNAJB6,
LOC100505921,
LRRC72,
ERHP1,
ATP5J2-PTCD1,
INMT-FAM188B,
ABCF2,
PTP4A1P3,
DUTP3,
CYP3A7-CYP3A51P,
ARPC1B,
C7orf55-LUC7L2,
NAMPT,
AKAP9,
RASA4,
AASS,
SLC25A13,
MEOX2-AS1,
CDK6,
LRRC17,
RAMP3,
BET1,
CCL26,
LOC103689914,
SEMA3A,
NOD1,
FAM3C,
GPNMB,
COG5,
ZNHIT1,
SEMA3C,
AGR2,
ARPC1A,
ADCY1,
NPM1P14,
NPM1P13,
PPP1R17,
DBF4,
KDELR2,
ZPBP,
HIBADH,
ZNF277,
INMT,
CHN2,
POU6F2,
GLCCI1,
PDAP1,
ZBED6CL,
DTX2,
WBSCR22,
AP1S1,
CLCN1,
TRIM50,
NOBOX,
OR6B1,
OR2F2,
MTPN,
CLDN4,
CLDN3,
C7orf31,
CRHR2,
RNF32,
CRYZP1,
CUX1,
C7orf55,
CCT8L1P,
RBM33,
CYP3A5,
CYP51A1,
DGKB,
GALNTL5,
RNF133,
BHLHA15,
DFNA5,
DLX5,
DLX6,
DYNC1I1,
DPP6
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 9847074 |
Toward a complete human genome sequence. Genome Res. Sanger Center , Genome Sequencing Center |
1998-11-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员