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7290 HIRA

7290

HIRA

histone cell cycle regulator

protein-coding

Homo sapiens

基因描述

Type Description
Definition histone cell cycle regulator

研究结论

Date Results Publications
2021-02-02 13:27:00 Two HIRA-dependent pathways mediate H3.3 de novo deposition and recycling during transcription. 32895554
2019-04-06 11:50:00 H3.3 chaperones HIRA and DAXX promote ectopic CENP-A deposition. 30365520
2019-01-12 10:44:00 analysis of the trimeric HIRA, UBN1 and CABIN1 H3.3 histone chaperone complex 30082790
2018-01-20 10:35:00 These data show that HIRA phosphorylation limits the expression of myogenic genes, while the dephosphorylation of HIRA is required for proficient H3.3 deposition and gene activation, demonstrating that the phosphorylation switch is exploited to modulate HIRA/H3.3-mediated muscle gene regulation during myogenesis. 27515126
2017-12-16 11:00:00 Data show that histone chaperone HIRA co-localizes with viral genomes, binds to incoming viral and deposits histone H3.3 onto these. 28981850

名称对应

Type IDs
Synonymous DGCR1, TUP1, TUPLE1
Gene
UniProtKB-ID: HIRA_HUMAN
UniprotKB: P54198
UniParc: UPI0000074373, UPI0000207B68
EMBL: BC032721, BC039835, X81844, X75296, CR456503, X91501, X89887, X77633
Ensembl: ENSG00000100084
KO: hsa:7290
Nucleutide sequences
EMBL-CDS: AAH32721.1, CAG30389.1, AAH39835.1, CAA53044.1, CAA57436.1, CAA62800.1, CAA61979.1, CAA54721.1
Ensembl_TRS: ENST00000340170, ENST00000263208
Protein sequencees
Ensembl_PRO: ENSP00000263208, ENSP00000345350
RefSeq: NP_003316.3
Others
UniRef100: UniRef100_P54198
UniRef90: UniRef90_P54198
UniRef50: UniRef50_P54198
UniGene: Hs.474206
CCDS: CCDS13759.1

全选

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研究热度

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