| Type | Description |
|---|---|
| Definition | Tu translation elongation factor, mitochondrial |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:15:00 | Elongation Factor Tu Switch I Element is a Gate for Aminoacyl-tRNA Selection. | 32061931 |
| 2018-11-24 10:24:00 | Novel mutation in mitochondrial Elongation Factor EF-Tu associated to dysplastic leukoencephalopathy and defective mitochondrial DNA translation. | 28132884 |
| 2018-03-03 10:27:00 | study revealed a novel role for TUFM as a host restriction factor that exerts an inhibitory effect on avian-signature PB2627E influenza virus propagation in human cells; found that increased TUFM-dependent autophagy correlates with the inhibitory effect on avian-signature influenza virus replication and may serve as a key intrinsic mechanism to restrict avian influenza virus infection in humans | 28611246 |
| 2017-11-04 11:56:00 | High expression of TUFM is associated with colorectal cancer. | 28449687 |
| 2017-09-02 13:35:00 | we identify a novel signaling hub centering on the NLRX1 TUFM protein complex, promoting autophagic flux. Defects in the expression of either NLRX1 or TUFM result in compromised autophagy when treated with EGFR inhibitors.These findings expand our understanding of the components involved in head and neck squamous cell carcinoma autophagy machinery that responds to EGFR inhibitors. | 26876213 |
| Type | IDs |
|---|---|
| Synonymous | COXPD4, EF-TuMT, EFTU, P43 |
| Gene |
UniProtKB-ID:
EFTU_HUMAN,
A0A384ME17_HUMAN
UniprotKB:
P49411,
A0A384ME17
UniParc:
UPI0000000C2F,
UPI0000049FD5
EMBL:
AC133550,
S75463,
L38995,
CH471267,
Y11797,
BC010041,
GQ901045,
BC001633,
X84694
Ensembl:
ENSG00000178952
KO:
hsa:7284
|
| Nucleutide sequences |
EMBL-CDS:
AAH01633.2,
CAA72493.1,
AAH10041.2,
AAC60647.1,
AAB00499.1,
CAA59169.1,
EAW51997.1,
ADO22562.1
Gene_ORFName:
hCG_1747191
Ensembl_TRS:
ENST00000313511
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000322439
RefSeq:
NP_001352289.1,
NP_003312.3
|
| Others |
UniRef100:
UniRef100_P49411
UniRef90:
UniRef90_P49411
UniRef50:
UniRef50_P49411
UniGene:
Hs.12084
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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