| Type | Description |
|---|---|
| Definition | cartilage acidic protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 12:35:00 | The neuronal overexpression of LOTUS in transgenic mice promotes motor recovery after spinal cord injury, and recombinant viral overexpression of LOTUS enhances retinal ganglion cell axonal regeneration after optic nerve crush. Thus, the level of LOTUS function titrates axonal regeneration. | 28935984 |
| 2017-07-29 13:11:00 | Genetic deletion of Crtac1 significantly inhibited cartilage degradation, osteophyte formation and gait abnormalities of post-traumatic OA in female, but not male, animals undergoing the destabilization of medial meniscus (DMM) surgery. | 27415616 |
| 2015-04-18 12:12:00 | These data suggest that LOTUS functions as a potent endogenous antagonist for NgR1 when bound by all four known NgR1 ligands. | 25034269 |
| 2012-04-14 10:48:00 | These findings suggest that the UA/EC region is a functional domain of LOTUS serving for an antagonistic action to NgR1. | 22281491 |
| 2011-08-20 10:49:00 | found CRTAC1-B(LOTUS)is key molecule for lateral olfactory tract(LOT)formation; NgR1 is LOTUS-binding protein;LOTUS suppressed Nogo-NgR1 binding and Nogo-induced growth cone collapse;suggest endogenous antagonism of NgR1 by LOTUS crucial for LOT formation | 21817055 |
| Type | IDs |
|---|---|
| Synonymous | 2810454P21Rik, AW047536, Crtac1B, Lotus |
| Gene |
UniProtKB-ID:
CRAC1_MOUSE
UniprotKB:
Q8R555
UniParc:
UPI00000286D1
EMBL:
AJ421516,
BC024472,
AK149069,
AK149020,
AK032328,
AK049801
Ensembl:
ENSMUSG00000042401
KO:
mmu:72832
|
| Nucleutide sequences |
EMBL-CDS:
BAC33924.1,
BAC27817.1,
AAH24472.1,
CAD13395.1,
BAE28721.1,
BAE28729.1
Ensembl_TRS:
ENSMUST00000048630
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044858
RefSeq:
XP_030106949.1,
XP_030106954.1,
XP_030106953.1,
XP_030106952.1,
NP_660105.3,
XP_006527434.2,
XP_030106950.1,
NP_001343517.1,
NP_001343518.1,
XP_006527432.2,
XP_030106951.1,
XP_006527435.1
|
| Others |
UniRef100:
UniRef100_Q8R555
UniRef90:
UniRef90_Q8R555
UniRef50:
UniRef50_Q9NQ79-3
UniGene:
Mm.313558
CCDS:
CCDS29828.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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