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7283 TUBG1

7283

TUBG1

tubulin gamma 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition tubulin gamma 1

研究结论

Date Results Publications
2021-02-06 13:58:00 Gravin-associated kinase signaling networks coordinate gamma-tubulin organization at mitotic spindle poles. 32732289
2020-05-09 12:16:00 TACC3 phosphorylation stabilizes gamma- tubulin ring complex assembly and thereby regulates formation of centrosomal asters. 31823729
2019-10-05 11:10:00 Data present two patients with novel de novo tubulin gamma 1 (TUBG1) mutations with milder neurodevelopmental disorders. 31151415
2019-06-15 12:28:00 Study investigated the consequences of four human malformations of cortical development-related TUBG1 variants by using in utero electroporation and a knock-in Tubg1Y92C/+ mouse model and show that pathogenic TUBG1 variants affect neuronal positioning by disrupting neuronal migration and affecting microtubule dynamics rather than centrosomal positioning or nucleation ability. 31086189
2019-05-11 11:02:00 Our findings suggest that level of gamma-tubulin expression may have an impact on patient survival at more advanced non-small cell lung cancer stages 30010174

名称对应

Type IDs
Synonymous CDCBM4, GCP-1, TUBG, TUBGCP1
Gene
UniProtKB-ID: TBG1_HUMAN
UniprotKB: P23258
UniParc: UPI0000136A56
EMBL: AK313339, BC000619, M61764, BT019931, CR407642
Ensembl: ENSG00000131462
KO: hsa:7283
Nucleutide sequences
EMBL-CDS: AAH00619.1, BAG36143.1, AAA52620.1, CAG28570.1, AAV38734.1
Ensembl_TRS: ENST00000251413
Protein sequencees
Ensembl_PRO: ENSP00000251413
RefSeq: NP_001061.2, XP_024306672.1
Others
UniRef100: UniRef100_P23258
UniRef90: UniRef90_P23258
UniRef50: UniRef50_P23258
UniGene: Hs.279669
CCDS: CCDS11433.1

全选

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研究热度

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