| Type | Description |
|---|---|
| Definition | ubiquitin associated and SH3 domain containing, B |
| Date | Results | Publications |
|---|---|---|
| 2019-07-27 12:08:00 | Bone marrow-derived dendritic cells (BMDCs) lacking Protein Tyrosine Phosphatase Sts-1 expression have an enhanced ability to inhibit Candida albicans growth and contribute significantly to the resistance of Sts-/- mice. Within BMDCs, the Sts phosphatases negatively regulate the activation of select pathways downstream of the key fungal pathogen pattern recognition receptor Dectin-1. | 30018105 |
| 2017-10-26 11:10:00 | Data suggest that Sts1 (suppressor of T-cell receptor signaling-1) negatively regulates TCR (T-cell receptor) signaling in activated T-lymphocytes via dephosphorylation of Zap70. | 24256567 |
| 2017-08-31 12:53:00 | Sts-1 and Sts-2 are not required for the immune control of murine herpesvirus 68 in a normal course of gammaherpesvirus infection. | 24587276 |
| 2017-06-24 11:24:00 | The absence of TULA-2 and also the relative level of TULA-2 expression modulates FcgammaRIIA-mediated platelet reactivity and heparin-induced thrombocytopenia in vivo. | 27765766 |
| 2017-05-27 12:08:00 | dephosphorylation of Tyr(P)(346) may be considered an important "checkpoint" in the regulation of Syk activation process. Putative biological functions of TULA-2-mediated dephosphorylation of Tyr(P)(346) may include deactivation of receptor-activated Syk or suppression of Syk activation by suboptimal stimulation. | 27609517 |
| Type | IDs |
|---|---|
| Synonymous | 2810457I06Rik, BB125008, STS-1, TULA-2, p70 |
| Gene |
UniProtKB-ID:
UBS3B_MOUSE
UniprotKB:
Q8BGG7
UniParc:
UPI00000EBA09,
UPI00000EB2A4
EMBL:
AK154576,
AK034450,
AK035764,
AK152013,
BC053436,
AK151895,
AK013361,
AB075602,
AK133948
Ensembl:
ENSMUSG00000032020
KO:
mmu:72828
|
| Nucleutide sequences |
EMBL-CDS:
AAH53436.1,
BAE32688.1,
BAC28714.1,
BAC29178.1,
BAC25403.1,
BAE30875.1,
BAD06450.1,
BAE30779.1,
BAE21945.1
Ensembl_TRS:
ENSMUST00000151485,
ENSMUST00000044155
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000116038,
ENSMUSP00000043865
RefSeq:
XP_006510695.1,
XP_006510699.1,
NP_001344341.1,
XP_030100498.1,
NP_789830.1,
XP_017169101.1
|
| Others |
UniRef100:
UniRef100_Q8BGG7
UniRef90:
UniRef90_Q8BGG7
UniRef50:
UniRef50_Q8TF42
UniGene:
Mm.133615
CCDS:
CCDS23085.1,
CCDS90541.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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