| Type | Description |
|---|---|
| Definition | alpha tocopherol transfer protein |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:07:00 | alpha-Tocopherol Transfer Protein Enhances alpha-Tocopherol Protective Effects in Lung A549 Cells. | 32469275 |
| 2019-08-31 12:10:00 | Low TTP expression is associated with liver fibrosis. | 30226813 |
| 2019-03-30 11:08:00 | Authors show that a novel interaction between TTP and the CCR4-NOT subunit, CNOT9, is required for recruitment of the deadenylase complex. In addition to CNOT1, CNOT9 is now included in the identified CCR4-NOT subunits shown to interact with TTP. | 29291391 |
| 2019-02-02 11:20:00 | Data show that, upon binding to its substrate, alpha-TTP acquires tendency to aggregation into thermodynamically stable high molecular weight oligomers with spheroidal particle formed by 24 protein monomers. Oligomerization is triggered by refolding of the N-terminus. These same oligomers are efficiently transported through an endothelial barrier and not through an epithelial one. | 28694484 |
| 2018-12-22 11:01:00 | alphaTTP does not appear to regulate the uptake and intracellular localization of different vitamin E congeners in cultured liver cells. | 30098456 |
| Type | IDs |
|---|---|
| Synonymous | ATTP, AVED, TTP1, alphaTTP |
| Gene |
UniProtKB-ID:
TTPA_HUMAN
UniprotKB:
P49638
UniParc:
UPI00001377AC
EMBL:
D49488,
BC058000,
U21938,
AH006950
Ensembl:
ENSG00000137561
KO:
hsa:7274
|
| Nucleutide sequences |
EMBL-CDS:
BAA08449.1,
AAC67490.1,
AAH58000.1,
AAA64309.1
Ensembl_TRS:
ENST00000260116
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000260116
RefSeq:
NP_000361.1,
XP_006716531.1
|
| Others |
UniRef100:
UniRef100_P49638
UniRef90:
UniRef90_P49638
UniRef50:
UniRef50_P49638
UniGene:
Hs.69049
CCDS:
CCDS6178.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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