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72709 C1qtnf6

72709

C1qtnf6

C1q and tumor necrosis factor related protein 6

protein-coding

Mus musculus

基因描述

Type Description
Definition C1q and tumor necrosis factor related protein 6

研究结论

Date Results Publications
2020-07-25 10:18:00 CTRP6 protected the heart from doxorubicin cardiotoxicity and improved cardiac function via activation of the AKT signaling pathway. 30719766
2019-04-27 12:20:00 CTRP6 knockdown protects against diet-induced obesity and promotes brown adipogenesis in mice. 29366805
2017-09-30 11:31:00 The results establish CTRP6 as a novel metabolic/immune regulator linking obesity to adipose tissue inflammation and insulin resistance. 28726640
2017-03-04 11:34:00 CTRP6 knockdown down-regulated the levels of lipogenic genes and phosphorylated Erk1/2 (p-Erk1/2) in the early lipogenic stage, whereas up-regulated p-Erk1/2 in the terminal differentiation in skeletal myoblasts. 27125977
2016-05-07 12:03:00 CTRP6 specifically suppresses the alternative pathway of the complement system. C1qtnf6(-/-) mice are highly susceptible to induced arthritis, Arthus reaction, and experimental autoimmune encephalomyelitis. 26404464

名称对应

Type IDs
Synonymous 2810036M19Rik, Adiq, CTRP6
Gene
UniProtKB-ID: C1QT6_MOUSE, A0A3B0IP29_MOUSE, A0A2R8W6P9_MOUSE
UniprotKB: Q6IR41, A0A3B0IP29, A0A2R8W6P9
UniParc: UPI0000192CB3, UPI0001549D79
EMBL: AL590144, AK154407, BC071187, AK051058, LT963065, DQ002399
Ensembl: ENSMUSG00000022440
KO: mmu:72709
Nucleutide sequences
EMBL-CDS: AAY21931.1, AAH71187.1, BAE32564.1, BAC34512.1, SOR70283.1
Ensembl_TRS: ENSMUST00000023075, ENSMUST00000229185
Protein sequencees
Ensembl_PRO: ENSMUSP00000023075, ENSMUSP00000155221
RefSeq: NP_001191081.1, XP_036015501.1, XP_006521518.1, XP_006521515.1, NP_082607.3, NP_001191082.1, XP_006521516.1, XP_036015502.1
Others
UniRef100: UniRef100_Q6IR41, UniRef100_A0A2R8W6P9
UniRef90: UniRef90_A0A2R8W6P9, UniRef90_Q6IR41
UniRef50: UniRef50_Q6IR41, UniRef50_A0A2R8W6P9
UniGene: Mm.34776
CCDS: CCDS37134.1

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