| Type | Description |
|---|---|
| Definition | transcription termination factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-26 11:46:00 | TTF1 expression is an independent predictor of survival of patients with advanced lung adenocarcinoma | 30348718 |
| 2018-12-22 10:11:00 | the TTF-1 protein and mRNA are specifically expressed in schwannomas | 29104109 |
| 2018-10-27 10:29:00 | Human TTF-I localizes in the nucleolus and N-terminus (1-224) of hTTF-I which include nucleolus localization sequence and the expression of Human TTF-I 521-732 increased HIV-I production by regulating transactivation of the LTR promoter. | 29555014 |
| 2018-10-06 11:22:00 | These findings collectively suggest that the triple combination of survivin knockdown with ABT-263 and trametinib treatment, may be a potential strategy for the treatment of KRAS-mutant lung adenocarcinoma. Furthermore, our findings indicate that the welldifferentiated type of KRAS-mutant lung tumors depends, at least in part, on TTF1 for growth. | 29658609 |
| 2018-09-22 10:16:00 | TTF-1 expression may serve as a predictive marker to identify lung cancer patients who may benefit from the addition of bevacizumab to platinum doublet therapy. | 30194207 |
| Type | IDs |
|---|---|
| Synonymous | TTF-1, TTF-I |
| Gene |
UniProtKB-ID:
TTF1_HUMAN,
A0A024R8C1_HUMAN,
A0A087WY09_HUMAN
UniprotKB:
Q15361,
A0A024R8C1,
A0A087WY09
UniParc:
UPI00020700CD,
UPI00001B55A7
EMBL:
BC127670,
BC143048,
BC062692,
BC127669,
CH471090,
X83973,
AL353701,
BC104639,
BC143049,
BC050734
Ensembl:
ENSG00000125482
KO:
hsa:7270
|
| Nucleutide sequences |
EMBL-CDS:
AAI04640.1,
CAA58807.1,
AAI43050.1,
AAI43049.1,
AAI27670.1,
AAH50734.1,
AAI27671.1,
AAH62692.1,
EAW88001.1,
EAW88002.1
Gene_ORFName:
hCG_31461
Ensembl_TRS:
ENST00000334270,
ENST00000612514
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000333920,
ENSP00000481441
RefSeq:
XP_006717336.2,
NP_031370.2,
NP_001192225.1
|
| Others |
UniRef100:
UniRef100_Q15361
UniRef90:
UniRef90_Q15361
UniRef50:
UniRef50_Q15361
UniGene:
Hs.54780,
Hs.732733
CCDS:
CCDS6948.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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