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72692 Hnrnpll

72692

Hnrnpll

heterogeneous nuclear ribonucleoprotein L-like

protein-coding

Mus musculus

基因描述

Type Description
Definition heterogeneous nuclear ribonucleoprotein L-like

研究结论

Date Results Publications
2018-07-28 11:49:00 HNRNPLL is a novel metastasis suppressor of colorectal cancer, and modulates alternative splicing of CD44 during epithelial-mesenchymal transition. 28360095
2017-08-12 12:07:00 Data suggest that hnRNPLL specifically associates with cytoplasmic PABPC1 in both T-lymphocytes and plasma cells; PABPC1 promotes binding of hnRNPLL to immunoglobulin H (IgH, heavy chain) mRNA and regulates switching from mIgH (membrane isoform) to sIgH (secreted isoform) in plasma cells. (hnRNPLL = heterogeneous nuclear ribonucleoprotein L-like protein; PABPC1 = cytoplasmic poly[A]-binding protein 1) 28611064
2016-05-14 10:19:00 We identify similar patterns of hnRNPLL-induced differential intron retention flanking alternative exons in 14 other genes, representing novel elements of the hnRNPLL-induced splicing program in T cells. 24476532
2015-07-25 11:10:00 Data indicate that the RNA-binding protein hnRNPLL has a critical role in tuning transcriptomes of terminally differentiating B lymphocytes. 25825742
2013-01-05 10:45:00 The splicing factor hnRNPLL and the transcription elongation factor ELL2 modulate the ratio of secred versus membrane-encoding Ighg2b transcripts at the expense of the secreted isoform. 22991471

名称对应

Type IDs
Synonymous 2510028H02Rik, 2810036L13Rik, AI256697, AI852082, Hnrpll
Gene
UniProtKB-ID: HNRLL_MOUSE
UniprotKB: Q921F4
UniParc: UPI00000EB7C6, UPI00003780F9, UPI00001EBB26
EMBL: BC071184, BC012849, AK146879, BC004763, AK034860
Ensembl: ENSMUSG00000024095
KO: mmu:72692
Nucleutide sequences
EMBL-CDS: AAH71184.1, BAE27500.1, AAH04763.1, AAH12849.2, BAC28858.1
Ensembl_TRS: ENSMUST00000061331, ENSMUST00000184635
Protein sequencees
Ensembl_PRO: ENSMUSP00000139372, ENSMUSP00000058308
RefSeq: NP_659051.3
Others
UniRef100: UniRef100_Q921F4
UniRef90: UniRef90_Q921F4
UniRef50: UniRef50_Q8WVV9
UniGene: Mm.64579
CCDS: CCDS70845.1

全选

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