| Type | Description |
|---|---|
| Definition | tetratricopeptide repeat domain 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:50:00 | Overexpressed TTC3 Protein Tends to be Cleaved into Fragments and Form Aggregates in the Nucleus. | 30203323 |
| 2020-06-06 11:33:00 | Data suggest that TTC3 may contribute to TGF-beta1-induced EMT and myofibroblast differentiation, potentially through SMURF2 ubiquitylation/proteasomal degradation and subsequent inhibition of SMURF2-mediated suppression of SMAD2 and SMAD3, which in turn induces TTC3 expression. | 30696809 |
| 2018-05-19 11:48:00 | USP16 and TTC3 were dysregulated in all affected human cells and two mouse models of Down syndrome. | 27586445 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| 2010-02-01 11:44:00 | Interaction between TTC3 and Akt may contribute to the clinical symptoms of Down syndrome. | 20059950 |
| Type | IDs |
|---|---|
| Synonymous | DCRR1, RNF105, TPRDIII |
| Gene |
UniProtKB-ID:
TTC3_HUMAN
UniprotKB:
P53804
UniParc:
UPI0000EE4CF7,
UPI0000EE4CD8,
UPI00001B043E
EMBL:
D84294,
AP001432,
D83327,
AP001429,
D84296,
CH471079,
BC063033,
BC092466,
AJ001866,
D83077,
D84295,
BC137345,
AK291992
Ensembl:
ENSG00000182670
KO:
hsa:7267
|
| Nucleutide sequences |
EMBL-CDS:
BAA12301.1,
EAX09720.1,
EAX09716.1,
BAA12303.1,
AAH92466.1,
EAX09718.1,
BAF84681.1,
CAA05057.1,
EAX09721.1,
BAA23666.1,
EAX09717.1,
BAA12302.1,
EAX09723.1,
AAH63033.1,
BAA11769.1,
EAX09722.1,
AAI37346.1,
EAX09719.1
Ensembl_TRS:
ENST00000354749,
ENST00000399017,
ENST00000355666
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347889,
ENSP00000346791,
ENSP00000381981
RefSeq:
XP_011528042.1,
NP_001340865.1,
NP_001340867.1,
XP_005261109.1,
NP_003307.3,
XP_005261107.1,
NP_001317612.1,
XP_005261111.1,
XP_005261113.1,
NP_001317610.1,
XP_016883950.1,
NP_001307632.1,
NP_001307633.1,
XP_016883949.1,
NP_001340866.1,
XP_016883954.1,
XP_011528041.1,
XP_005261112.1,
XP_005261105.1,
NP_001001894.1,
XP_016883948.1,
XP_005261106.1,
NP_001317611.1,
XP_016883947.1,
XP_016883951.1
|
| Others |
UniRef100:
UniRef100_P53804
UniRef90:
UniRef90_P53804
UniRef50:
UniRef50_P53804
UniGene:
Hs.368214
CCDS:
CCDS13651.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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