| Type | Description |
|---|---|
| Definition | tetratricopeptide repeat domain 1 |
| Date | Results | Publications |
|---|---|---|
| 2013-02-09 11:38:00 | TPR1 is required for Galpha14 to stimulate Ras-dependent signaling pathways, but not for the propagation of signals along Ras-independent pathways. | 22711498 |
| 2013-01-26 10:21:00 | The crystal structure of monopolar spindle 1 (Mps1) N-terminal region TPR domain has been determined. | 23067341 |
| 2011-09-17 10:16:00 | beta3 region of Galpha16 is essential for interaction with TPR1 and the subsequent activation of Ras | 21486497 |
| 2010-01-21 00:00:00 | Data show that tetratricopeptide repeat 1 is a novel adaptor protein for Ras and selected Galpha proteins that may be involved in protein-protein interaction relating to G-protein signaling. | 12748287 |
| 2010-01-21 00:00:00 | Results report cooperative interactions involving Hsp70, Hsp40, and TPR1 that enhance Hsp70-dependent folding of chemically denatured substrates. | 14503850 |
| Type | IDs |
|---|---|
| Synonymous | TPR1 |
| Gene |
UniProtKB-ID:
TTC1_HUMAN
UniprotKB:
Q99614
UniParc:
UPI0000030D6C
EMBL:
CH471062,
AK315262,
BC000942,
U46570
Ensembl:
ENSG00000113312
KO:
hsa:7265
|
| Nucleutide sequences |
EMBL-CDS:
BAG37679.1,
AAH00942.1,
AAB36871.1,
EAW61571.1,
EAW61570.1
Ensembl_TRS:
ENST00000522793,
ENST00000231238
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000429225,
ENSP00000231238
RefSeq:
NP_001269429.1,
NP_003305.1
|
| Others |
UniRef100:
UniRef100_Q99614
UniRef90:
UniRef90_Q99614
UniRef50:
UniRef50_Q99614
UniGene:
Hs.519718
CCDS:
CCDS4348.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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