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72634 Tdrkh

72634

Tdrkh

tudor and KH domain containing protein

protein-coding

Mus musculus

基因描述

Type Description
Definition tudor and KH domain containing protein

研究结论

Date Results Publications
2019-10-19 10:54:00 we show that mitochondria-anchored TDRKH controls multiple steps of pachytene piRNA biogenesis in mice. TDRKH specifically recruits MIWI, but not MILI, to engage the piRNA pathway. It is required for the production of the entire MIWI-bound piRNA population and enables trimming of MILI-bound piRNAs. 30590800
2018-06-23 11:44:00 Unlike most other Tudor domains TDRD2 preferentially recognizes an unmethylated arginine-rich sequence from PIWIL1. 29118143
2013-09-07 11:45:00 Loss of Tdrkh is associated with impaired spermatogenesis. 23714778

名称对应

Type IDs
Synonymous 2700091C21Rik, Tdrd2
Gene
UniProtKB-ID: TDRKH_MOUSE
UniprotKB: Q80VL1
UniParc: UPI0000171B9C
EMBL: BC049363, GL456099
Ensembl: ENSMUSG00000041912
KO: mmu:72634
Nucleutide sequences
EMBL-CDS: AAH49363.1
Ensembl_TRS: ENSMUST00000197901, ENSMUST00000045245, ENSMUST00000166032
Protein sequencees
Ensembl_PRO: ENSMUSP00000041002, ENSMUSP00000142561, ENSMUSP00000129635
RefSeq: NP_001344642.1, XP_030108703.1, NP_001344643.1, NP_082583.1, NP_001344641.1, NP_001344640.1
Others
UniRef100: UniRef100_Q80VL1
UniRef90: UniRef90_Q80VL1
UniRef50: UniRef50_Q80VL1
UniGene: Mm.331198, Mm.470795
CCDS: CCDS38534.1

全选

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