| Type | Description |
|---|---|
| Definition | pleckstrin homology like domain family A member 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:49:00 | PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway. | 32385195 |
| 2020-12-19 13:42:00 | PHLDA2 gene polymorphisms and risk of HELLP syndrome and severe preeclampsia. | 32062476 |
| 2020-03-14 12:53:00 | Increased CDKN1C and PHLDA2 and reduced IGF-2 abundances in placental tissue were related to BW and early period catch-up growth in full-term SGA infants. | 31194812 |
| 2019-03-30 11:14:00 | Authors demonstrated that TSSC3 was an independent prognostic marker for overall survival in osteosarcoma, and positive ATG5 expression associated with positive TSSC3 expression suggested a favorable prognosis for patients. Then, we showed that TSSC3 overexpression enhanced autophagy via inactivating the Src-mediated PI3K/Akt/mTOR pathway in osteosarcoma. | 30092789 |
| 2017-10-14 11:38:00 | RanBP9/TSSC3 complex cooperatively suppress metastasis via downregulation of Src-dependent Akt pathway to expedite mitochondrial-associated anoikis. | 28032865 |
| Type | IDs |
|---|---|
| Synonymous | BRW1C, BWR1C, HLDA2, IPL, TSSC3 |
| Gene |
UniProtKB-ID:
PHLA2_HUMAN
UniprotKB:
Q53GA4
UniParc:
UPI0000072776
EMBL:
AK223027,
BC005034,
CR407664,
AF019953,
AF001294,
AF035444
Ensembl:
ENSG00000181649,
ENSG00000274538
KO:
hsa:7262
|
| Nucleutide sequences |
EMBL-CDS:
CAG28592.1,
AAH05034.1,
BAD96747.1,
AAB86680.1,
AAC17458.1,
AAC51912.1
Ensembl_TRS:
ENST00000618418,
ENST00000314222
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000319231,
ENSP00000483602
RefSeq:
NP_003302.1
|
| Others |
UniRef100:
UniRef100_Q53GA4
UniRef90:
UniRef90_Q53GA4
UniRef50:
UniRef50_O08969
UniGene:
Hs.154036
CCDS:
CCDS7741.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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