| Type | Description |
|---|---|
| Definition | testis specific protein Y-linked 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:28:00 | Epigenetic modification-dependent androgen receptor occupancy facilitates the ectopic TSPY1 expression in prostate cancer cells. | 33185915 |
| 2020-04-04 11:56:00 | Compared to n-TSPY, all other PCR assays had poor performance to detect semen exposure. The n-TSPY is an accessible assay that may have great utility in assessing semen exposure in studies where many factors are expected to accelerate biomarkers' clearance. | 31344101 |
| 2019-05-18 11:18:00 | Experimental evidence establishes TSPY1 as an oncogenic factor that facilitates tumor progression and causes poor prognosis in male patients with lung adenocarcinoma or hepatocellular carcinoma. These findings revealed that TSPY1 strongly promotes the activation of the PI3K/AKT and RAS signaling pathways through suppressing IGFBP3 gene transcription. | 30815935 |
| 2018-09-08 11:09:00 | The expression of spermatogenic phenotypes of TSPY1 defects is independent of variations in TSPYL1 and TSPYL5 in the Han Chinese population. | 28847364 |
| 2017-05-20 12:47:00 | TSPY and TSPX exert opposing effects on the transactivation functions of AR and AR-Vs important for various physiological and disease processes sensitive to male sex hormone actions, thereby not only affecting the pathogenesis of male-specific prostate cancer but also likely contributing to sex differences in the health and diseases of man. | 28169398 |
| Type | IDs |
|---|---|
| Synonymous | CT78, DYS14, TSPY, pJA923 |
| Gene |
UniProtKB-ID:
TSPY1_HUMAN,
A4FUW6_HUMAN
UniprotKB:
Q01534,
A4FUW6
UniParc:
UPI0000F5852D,
UPI0000140E1A,
UPI0001E5EA75
EMBL:
AF106331,
M94893,
M98524,
AC006156,
U58096,
X74029,
BC121113,
BC121114,
X06325,
M98525
Ensembl:
ENSG00000258992
KO:
hsa:728137,
hsa:7258,
hsa:100289087
|
| Nucleutide sequences |
EMBL-CDS:
AAB51693.1,
AAA61238.1,
AAI21115.1,
CAA29640.1,
AAD47421.1,
AAA36570.1,
AAI21114.1
Ensembl_TRS:
ENST00000451548,
ENST00000423647
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000389324,
ENSP00000403304
RefSeq:
NP_001307893.1,
NP_003299.2,
XP_016885553.1,
NP_001184171.1
|
| Others |
UniRef100:
UniRef100_A4FUW6,
UniRef100_Q01534
UniRef90:
UniRef90_Q01534,
UniRef90_A0A2I3RCZ3
UniRef50:
UniRef50_Q01534,
UniRef50_A0A2I3RCZ3
UniGene:
Hs.556121,
Hs.647493
CCDS:
CCDS48205.1,
CCDS76071.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员