| Type | Description |
|---|---|
| Definition | T cell activation Rho GTPase activating protein |
| Date | Results | Publications |
|---|---|---|
| 2020-08-13 17:13:00 | TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response. | 32312989 |
| 2019-10-05 10:57:00 | Loss of Tagap in mice suppressed the sema3E- and plexin-D1-mediated release of thymocytes that adhered within the cortex through beta1-containing integrins. This suppression led to the impaired translocation of thymocytes from the cortex to the medulla and resulted in the formation of ectopic medullary structures within the thymic cortex leading to autoimmune disorders. | 29895617 |
| 2019-05-04 10:46:00 | These findings indicate that increased TAGAP expression is a distinguishing feature of inflammatory disease and further highlight the role of TAGAP in rheumatoid arthritis susceptibility. | 29017772 |
| 2018-06-23 10:32:00 | these studies demonstrated that TAGAP was required for TH17 differentiation in vitro and that the loss of TAGAP in mice ameliorated the clinical features of experimental autoimmune encephalomyelitis, indicating that TAGAP is critical for disease progression | 28462950 |
| 2018-02-15 05:11:00 | Experimental and computational approaches yield a high-resolution, 1-Mb physical map of the region harboring the mouse t haplotype sterility factor, tcs1 | 11471064 |
| Type | IDs |
|---|---|
| Synonymous | 2610315E15Rik, TRD, Tcd-1, Tcd1, Tcd1a, tcs-1, tcs1 |
| Gene |
UniProtKB-ID:
TAGAP_MOUSE
UniprotKB:
B2RWW0
UniParc:
UPI000002876D
EMBL:
BC039780,
BC030886,
BC150728
Ensembl:
ENSMUSG00000033450
KO:
mmu:72536
|
| Nucleutide sequences |
EMBL-CDS:
AAH30886.1,
AAI50729.1,
AAH39780.1
Ensembl_TRS:
ENSMUST00000036370
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047431
RefSeq:
NP_666080.1,
XP_006523417.1
|
| Others |
UniRef100:
UniRef100_B2RWW0
UniRef90:
UniRef90_B2RWW0
UniRef50:
UniRef50_B2RWW0
UniGene:
Mm.119680
CCDS:
CCDS28379.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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