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72535 Aldh1b1

72535

Aldh1b1

aldehyde dehydrogenase 1 family, member B1

protein-coding

Mus musculus

基因描述

Type Description
Definition aldehyde dehydrogenase 1 family, member B1

研究结论

Date Results Publications
2020-05-02 11:25:00 We identified AMI-5, a protein methyltransferase inhibitor, as an Aldh1b1 inducer and showed that it can maintain Aldh1b1 expression in embryonic pancreas explants. This led to a selective reduction in endocrine specification. This effect was due to a downregulation of Ngn3, and it was mediated through Aldh1b1 since the effect was abolished in Aldh1b1 null pancreata. 30681750
2020-04-04 10:19:00 Overexpression of Aldh1b1 is associated with pancreatic cancer development. 31548432
2016-10-22 11:28:00 Aldehyde dehydrogenase has a critical role for beta cell development and functionality in mice 26518685
2015-11-07 10:27:00 show for the first time the functional in vivo role of ALDH1B1 in acetaldehyde metabolism and in maintaining glucose homeostasis 26086111
2013-03-16 10:24:00 ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools 23142317

名称对应

Type IDs
Synonymous 2700007F14Rik
Gene
UniProtKB-ID: AL1B1_MOUSE
UniprotKB: Q9CZS1
UniParc: UPI0000025CAC
EMBL: BC020001, AK012213, AK153416, AK151349, BC086768, AK088396, AK151364, AK150992
Ensembl: ENSMUSG00000035561
KO: mmu:72535
Nucleutide sequences
EMBL-CDS: BAE30016.1, BAE30325.1, BAC40326.1, BAB28101.1, BAE31976.1, AAH20001.1, BAE30339.1, AAH86768.1
Ensembl_TRS: ENSMUST00000044384
Protein sequencees
Ensembl_PRO: ENSMUSP00000041260
RefSeq: NP_082546.1
Others
UniRef100: UniRef100_Q9CZS1
UniRef90: UniRef90_P30837
UniRef50: UniRef50_P30837
UniGene: Mm.331583
CCDS: CCDS18139.1

全选

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研究热度

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