| Type | Description |
|---|---|
| Definition | tumor susceptibility 101 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:31:00 | An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D-TSG101 interactions. | 33623047 |
| 2020-12-19 13:43:00 | Proline-rich domain of human ALIX contains multiple TSG101-UEV interaction sites and forms phosphorylation-mediated reversible amyloids. | 32917811 |
| 2020-07-25 10:15:00 | Authors used CRISPR/Cas9-mediated knock-in to tag the critical ESCRT-I component tumor susceptibility 101 (Tsg101) with GFP at its native locus in two widely used human cell types, HeLa epithelial cells and Jurkat T cells. | 31519756 |
| 2020-07-25 10:13:00 | This study shows that SH3YL1 cooperates with ESCRT-I in the sorting and degradation of the EGF receptor. | 31492760 |
| 2020-05-16 11:30:00 | We found that inhibition of CD133 complex-type N-glycosylation by swainsonine does not affect the membrane localization of CD133, but significantly reduces CD133 secretion and promotes its accumulation in early endosomes. Moreover, swainsonine reduces CD133 secretion by reducing its mono-ubiquitination and inhibiting the interaction between CD133 and Tsg101. | 30873590 |
| Type | IDs |
|---|---|
| Synonymous | TSG10, VPS23 |
| Gene |
UniProtKB-ID:
TS101_HUMAN
UniprotKB:
Q99816
UniParc:
UPI000002B49A,
UPI000004750C
EMBL:
BC002487,
U82130
Ensembl:
ENSG00000074319
KO:
hsa:7251
|
| Nucleutide sequences |
EMBL-CDS:
AAH02487.1,
AAC52083.1
Ensembl_TRS:
ENST00000251968
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000251968
RefSeq:
XP_005253165.1,
NP_006283.1
|
| Others |
UniRef100:
UniRef100_Q99816
UniRef90:
UniRef90_Q99816
UniRef50:
UniRef50_Q99816
UniGene:
Hs.523512
CCDS:
CCDS7842.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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