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72508 Rps6kb1

72508

Rps6kb1

ribosomal protein S6 kinase, polypeptide 1

protein-coding

Mus musculus

基因描述

Type Description
Definition ribosomal protein S6 kinase, polypeptide 1

研究结论

Date Results Publications
2021-03-20 13:28:00 High mobility group box 2 regulates skeletal muscle development through ribosomal protein S6 kinase 1. 32686868
2020-12-05 12:59:00 Deficiency of the oxidative stress-responsive kinase p70S6K1 restores autophagy and ameliorates neural tube defects in diabetic embryopathy. 32416155
2020-11-21 13:15:00 Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington's disease. 31695068
2020-09-26 13:08:00 OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance. 32601203
2019-12-14 12:38:00 Our data demonstrated that S6K1 was the downstream effector of mTOR and that S6K1 was critical for both rod and cone survival in Retinitis pigmentosa (RP). Our findings make a strong case for targeting S6K1 as a promising therapeutic strategy for promoting the survival of photoreceptors in RP 30442943

名称对应

Type IDs
Synonymous 2610318I15Rik, AA959758, AI256796, AI314060, P70S6K1, S6K, S6K-beta-1, S6K1, p70 S6K-alpha, p70 S6KA, p70-S6K 1, p70/85s6k, p70s6k
Gene
UniProtKB-ID: KS6B1_MOUSE, Q3UXD8_MOUSE, Q8C3J7_MOUSE
UniprotKB: Q8BSK8, Q3UXD8, Q8C3J7
UniParc: UPI00000E8D05, UPI00000E9EFC, UPI00005ABBCA, UPI00004CABED
EMBL: AK032724, AK135716, AK085687, CH466556, AL604063, BC038491
Ensembl: ENSMUSG00000020516
KO: mmu:72508
Nucleutide sequences
EMBL-CDS: EDL15788.1, BAC28000.1, AAH38491.1, BAE22625.1, BAC39506.1
Ensembl_TRS: ENSMUST00000154617, ENSMUST00000058286
Protein sequencees
Ensembl_PRO: ENSMUSP00000119715, ENSMUSP00000053188
RefSeq: XP_036012909.1, NP_001350091.1, XP_011247578.1, XP_036012907.1, XP_036012908.1, XP_036012911.1, XP_036012910.1, NP_001107806.1, XP_006534378.1, XP_011247577.1, NP_082535.1
Others
UniRef100: UniRef100_Q3UXD8, UniRef100_Q8C3J7, UniRef100_Q8BSK8
UniRef90: UniRef90_P67999, UniRef90_Q8C3J7
UniRef50: UniRef50_Q8C3J7, UniRef50_P67999
UniGene: Mm.394280, Mm.446624, Mm.479484
CCDS: CCDS48875.1

全选

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