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72461 Prcp

72461

Prcp

prolylcarboxypeptidase (angiotensinase C)

protein-coding

Mus musculus

基因描述

Type Description
Definition prolylcarboxypeptidase (angiotensinase C)

研究结论

Date Results Publications
2019-03-16 12:50:00 PRCP in Agouti-related peptide neurons contributes to the modulation of alpha-MSH degradation, food intake and body weight. 29459251
2018-02-24 11:51:00 Prolylcarboxypeptidase (PRCP) converts AngII to Ang (1-7) but only at an acidic pH. Global PRCP deficiency causes heart and kidney alterations and a moderate rise in BP. PRCP is abundant in the kidney collecting tubules, where the prevailing pH is low. In collecting tubules, PRCP deficiency could result in impaired AngII degradation. Increased AngII at this nephron site stimulates Na reabsorption and increases BP. 28160049
2017-12-16 11:23:00 activity and expression in plasma and lung tissue stays unaffected in lung ischemia-reperfusion injury 27437782
2014-08-16 12:33:00 This study demonistrated that PRCP gene is broadly expressed in the brain. 24161824
2013-11-16 11:54:00 PRCP regulates cell growth, angiogenesis, and the response to vascular injury 23744584

名称对应

Type IDs
Synonymous 2510048K03Rik, 2610104A14Rik, AI451719, HUMPCP, PCP
Gene
UniProtKB-ID: PCP_MOUSE
UniprotKB: Q7TMR0
UniParc: UPI0000024BC0, UPI00000EB57A
EMBL: AK011816, BC055022, BC026424, AK051677, AK166282, AK054462
Ensembl: ENSMUSG00000061119
KO: mmu:72461
Nucleutide sequences
EMBL-CDS: AAH55022.1, BAE20697.1, BAE38679.1, BAC34716.1, AAH26424.1, BAB27858.1
Ensembl_TRS: ENSMUST00000076052
Protein sequencees
Ensembl_PRO: ENSMUSP00000075429
RefSeq: NP_082519.1
Others
UniRef100: UniRef100_Q7TMR0
UniRef90: UniRef90_Q7TMR0
UniRef50: UniRef50_Q7TMR0
UniGene: Mm.389969
CCDS: CCDS21452.1

全选

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研究热度

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