Type | Description |
---|---|
Definition | prolylcarboxypeptidase (angiotensinase C) |
Date | Results | Publications |
---|---|---|
2019-03-16 12:50:00 | PRCP in Agouti-related peptide neurons contributes to the modulation of alpha-MSH degradation, food intake and body weight. | 29459251 |
2018-02-24 11:51:00 | Prolylcarboxypeptidase (PRCP) converts AngII to Ang (1-7) but only at an acidic pH. Global PRCP deficiency causes heart and kidney alterations and a moderate rise in BP. PRCP is abundant in the kidney collecting tubules, where the prevailing pH is low. In collecting tubules, PRCP deficiency could result in impaired AngII degradation. Increased AngII at this nephron site stimulates Na reabsorption and increases BP. | 28160049 |
2017-12-16 11:23:00 | activity and expression in plasma and lung tissue stays unaffected in lung ischemia-reperfusion injury | 27437782 |
2014-08-16 12:33:00 | This study demonistrated that PRCP gene is broadly expressed in the brain. | 24161824 |
2013-11-16 11:54:00 | PRCP regulates cell growth, angiogenesis, and the response to vascular injury | 23744584 |
Type | IDs |
---|---|
Synonymous | 2510048K03Rik, 2610104A14Rik, AI451719, HUMPCP, PCP |
Gene |
UniProtKB-ID:
PCP_MOUSE
UniprotKB:
Q7TMR0
UniParc:
UPI0000024BC0,
UPI00000EB57A
EMBL:
AK011816,
BC055022,
BC026424,
AK051677,
AK166282,
AK054462
Ensembl:
ENSMUSG00000061119
KO:
mmu:72461
|
Nucleutide sequences |
EMBL-CDS:
AAH55022.1,
BAE20697.1,
BAE38679.1,
BAC34716.1,
AAH26424.1,
BAB27858.1
Ensembl_TRS:
ENSMUST00000076052
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000075429
RefSeq:
NP_082519.1
|
Others |
UniRef100:
UniRef100_Q7TMR0
UniRef90:
UniRef90_Q7TMR0
UniRef50:
UniRef50_Q7TMR0
UniGene:
Mm.389969
CCDS:
CCDS21452.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员