| Type | Description |
|---|---|
| Definition | serine peptidase inhibitor, Kazal type 5 |
| Date | Results | Publications |
|---|---|---|
| 2011-01-01 10:42:00 | Spink5/Par2 double knockout (DKO) mice, at embryonic day 19.5, display a dramatic decrease in TSLP expression, although stratum corneum detachment persists, confirming the role of the KLK5-PAR2 cascade in TSLP-mediated early proallergic signaling | 20703245 |
| 2010-01-21 00:00:00 | key regulator of epidermal protease activity | 15619623 |
| 2010-01-21 00:00:00 | Mouse Spink5/Lekti, like its human counterpart, is involved in the control of epithelial tissue homeostasis. | 15780751 |
| Type | IDs |
|---|---|
| Synonymous | 2310065D10Rik, AV238912, LEKT1, LETK1, VAKT1 |
| Gene |
UniProtKB-ID:
Q148R4_MOUSE
UniprotKB:
Q148R4
UniParc:
UPI00001C60B4
EMBL:
BC118011,
AC138293
Ensembl:
ENSMUSG00000055561
KO:
mmu:72432
|
| Nucleutide sequences |
EMBL-CDS:
AAI18012.1
Ensembl_TRS:
ENSMUST00000069245
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000066214
RefSeq:
XP_006526343.1,
NP_001074649.1,
XP_006526342.1
|
| Others |
UniRef100:
UniRef100_Q148R4
UniRef90:
UniRef90_Q148R4
UniRef50:
UniRef50_Q9NQ38
UniGene:
Mm.35369
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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